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Article
Open AccessPAM-flexible Engineered FnCas9 variants for robust and ultra-precise genome editing and diagnostics
The clinical success of CRISPR therapies hinges on the safety and efficacy of Cas proteins. The Cas9 from Francisella novicida (FnCas9) is highly precise, with a negligible affinity for mismatched substrates, but...
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Article
Role of consistent regime-specific policies in recovering the negative relationship between financial development and economic growth
This synopsis empirically showed that the negative relationship between financial development and economic growth can be reversed through consistent policies in Pakistan. To empirically test this argument, the...
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Article
Open AccessIdentifying and ranking of CMIP6-global climate models for projected changes in temperature over Indian subcontinent
Selecting the best region-specific climate models is a precursor information for quantifying the climate change impact studies on hydraulic/hydrological projects and extreme heat events. A crucial step in lowe...
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Article
Open AccessThe investigation of diesel soot emission using instrument combination of multi-wavelength photoacoustic spectroscopy and scanning mobility particle sizer
The parallel measurements of wavelength dependent optical absorption, particle number size distribution have made by a multi wavelength photoacoustic spectrometer (4λ-PAS) and scanning mobility particle sizer ...
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Chapter and Conference Paper
Additive Manufacturing of Magnesium Alloys for Biomedical Applications
Magnesium alloys, with their stiffness comparable with that of bone, might serve as a new class of biodegradable materials that reduce the adverse effects of stress shielding. Due to its biodegradability, magn...
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Article
COVID-19 and Neurodevelopmental Disabilities: Examining the Impact of the First 2 Years of the Pandemic on the Demand for Pediatric Inpatient Care
The COVID-19 pandemic has strained the resources of the world’s healthcare systems. Most individuals with neurodevelopmental disabilities (NDDs) experience significant mental health issues and face substantial...
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Article
The Relationship Between Financial Development and Economic Growth: New Insights Using Quadruple and Quintuple Helix Innovation Framework and Way Forward
In this study, we showed that the spurts and reversals in GDP growth can be reinvented through consistency in financial and real sector policies along with the strengthening of knowledge democracy, and quality...
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Chapter and Conference Paper
Transformation of an Esvecees (SVCS) Value to Spherical Coordinates as the Result of the Earthquake Forecasting Using SLHGN
The main issue, which has existed since the development of Single Layer Hierarchical Graph Neuron (SLHGN) started, is the representation for location data that will be fed to SLHGN structure. Similar issue, th...
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Chapter and Conference Paper
The Role of Quasi-static Strain Rate on the Mechanical Behaviour of WE43 Magnesium Alloy
Magnesium alloy WE43 has quickly become the material of choice for use in aviation, vehicles and medical implant technology. In this study, the influence of quasi-static loading rate on the mechanical characte...
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Chapter
AI for Cyberbiosecurity in Water Systems—A Survey
The use of Artificial Intelligence (AI) is growing in areas where decisions and consequences have high-stakes such as larger scale software, critical infrastructure, and real-time systems. This transition in r...
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Chapter
Floristic Inventory of Ethnobotanically Important Plants of Thangy Dara District Dir Lower Khyber Pakhtunkhwa, Pakistan
Thangy dara (34° 38 to 35° 52´ N and 71° 45 to 71° 59´ E) is a rural area in District Dir, lower Pakistan, with a population of 878 (434 male and 444 females). The area includes Sino-Japanese floral elements. ...
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Chapter
Seaweed Cultivation Technologies in Indonesia: Current Trends and Future Prospects
Seaweed is one of the important commodities in marine cultivation. In this chapter, we describe horizontal net (HN) and vertical net (VN), a technological innovation that can protect seaweed from various attac...
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Chapter and Conference Paper
Analysing the Academic Performance of Students Under Varying Climatic Conditions
The impact of climate change can be easily recognized around the world. With the sudden increase in carbon emission in recent years, it is been noted that working in an open environment is getting harder. To t...
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Article
Synthesis of novel nicotinamide susbstituted phthalocyanine and photodynamic antomicrobial chemotherapy evaluation potentiated by potassium iodide against the gram positive S. aureus and gram negative E. coli
In the present work, we propose the synthesis of novel nicotinamide subsituted phthlocyanine photosensitizer (PS) and characterized by FTIR, UV–visible, H-NMR and MALDI Toff spectroscopy. Nicotinamide plays a ...
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Article
Bisindole alkaloids from Voacanga grandifolia leaves
Two new bisindole alkaloids, 12′-O-demethyl-vobtusine-5-lactam and isovobtusine-N-oxide (1 and 2), were isolated from the leaves of Voacanga grandifolia, together with two known bisindole alkaloids. Their structu...
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Article
Improved optical and electrochemical performance of MoS2-incorporated TiO2-PbS nanocomposite for solar paint application
Solar paint-based quantum dot-sensitized solar cells are promising low-cost photovoltaic devices. However, due to various detrimental optoelectronic features including poor transfer and higher recombination of...
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Article
Restrictive versus facilitative teacher professional development: a case from three public schools in Indonesia
This paper argues that the professional learning of teachers is shaped and conditioned by the circumstances, arrangements, and specificity of teacher professional development (TPD) learning activities or progr...
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Article
Face sketch recognition: an application of Z-numbers
To simulate the capability of human decision making with rationality on a machine is a quite difficult task. In the seminal line the automation of sketching of face involves computation of words and propositio...
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Chapter and Conference Paper
Globally Optimization Energy Grid Management System
This paper focuses on the smart grid with cloud and fog computing to reduce the wastage of electricity. A traditional grid is converted into a smart grid to reduce the increase of temperature. A smart grid is ...
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Chapter and Conference Paper
Efficient Resource Distribution in Cloud and Fog Computing
Smart Grid (SG) is a modern electrical grid with the combination of traditional grid and Information, Communication and Technology. SG includes various energy measures including smart meters and energy-efficie...