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No evidence of white adipocyte browning after endurance exercise training in obese men
The phenomenon of adipocyte ‘beiging’ involves the conversion of non-classic brown adipocytes to brown-like adipose tissue with thermogenic, fat-burning properties, and this phenomenon has been shown in rodent...
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Article
Ephedrine activates brown adipose tissue in lean but not obese humans
Brown adipose tissue (BAT) activation increases energy consumption and may help in the treatment of obesity. Cold exposure is the main physiological stimulus for BAT thermogenesis and the sympathetic nervous s...
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Novel pharmacological approaches to combat obesity and insulin resistance: targeting skeletal muscle with ‘exercise mimetics’
Chronic diseases arising from obesity will continue to escalate over coming decades. Current approaches to combating obesity include lifestyle measures, surgical interventions and drugs that target weight redu...
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Article
The Spectral Shift Function and Spectral Flow
At the 1974 International Congress, I. M. Singer proposed that eta invariants and hence spectral flow should be thought of as the integral of a one form. In the intervening years this idea has lead to many int...
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Discordant gene expression in skeletal muscle and adipose tissue of patients with type 2 diabetes: effect of interleukin-6 infusion
We compared metabolic gene expression in adipose tissue and skeletal muscle from patients with type 2 diabetes and from well-matched healthy control subjects. We hypothesised that gene expression would be disc...
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Hormone-sensitive lipase is reduced in the adipose tissue of patients with type 2 diabetes mellitus: influence of IL-6 infusion
Type 2 diabetes mellitus is characterised by increased plasma NEFA and IL-6 concentrations, and IL-6 increases lipolysis in healthy men. We assessed the adipose tissue hormone-sensitive lipase (HSL) mRNA expre...
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Interleukin-6 and insulin sensitivity: friend or foe?
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Interleukin-6 and tumor necrosis factor-α are not increased in patients with Type 2 diabetes: evidence that plasma interleukin-6 is related to fat mass and not insulin responsiveness
Our aim was to examine the possible direct relationship of interleukin-6 and TNFα with insulin sensitivity in humans.
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Article
Quantum Group Actions on the Cuntz Algebra
The Cuntz Algebra carries in a natural way the structure of a module algebra over the quantized universal envelo** algebra U q ...
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Article
Quantum Hall Effect on the Hyperbolic Plane
In this paper, we study both the continuous model and the discrete model of the Quantum Hall Effect (QHE) on the hyperbolic plane. The Hall conductivity is identified as a geometric invariant associated to an ...
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Article
Seiberg--Witten Monopoles in Three Dimensions
Dimensional reduction of the Seiberg--Witten equations leads to the equations of motion of a U(1) Chern--Simons theory coupled to a massless spinorial field. A topological quantum field theory is constructed f...
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Article
Quantum groups at odd roots of unity and topological invariants of 3-manifolds
Topological invariants of three-manifolds are constructed using quantum groups associated with theA, B, C andD series of Lie algebras at odd roots of unity. These invariants are also explicitly computed for the l...
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Article
Faddeev's anomaly and bundle gerbes
We show that transgression of the Dixmier-Douady class coming from the natural gerbe arising in the discussion of Faddeev's anomaly is the Faddeev-Mickelsson 2-cocycle.
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Article
Infinite dimensional groups and Riemann surface field theories
We show how to obtain positive energy representations of the groupG of smooth maps from a union of circles toU(N) from geometric data associated with a Riemann surface having these circles as boundary. Using cove...
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Group actions on C*-algebras, 3-cocycles and quantum field theory
We study group extensions Δ→Γ→Ω, where Γ acts on a C*-algebraA. Given a twisted covariant representation π,V of the pairA, Δ we construct 3-cocycles on Ω with values in the centre of the group generated byV(Δ). T...
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A Kirillov theory for divisible nilpotent groups
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The Landau-Lifshitz equation, elliptic curves and the ward transform
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The Landau-Lifshitz equation, elliptic curves and the Ward transform
The Landau-Lifshitz (LL) equation is studied from a point of view that is close to that of Segal and Wilson's work on KdV. The LL hierarchy is defined and shown to exist using a dressing transformation that in...
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Finite-dimensional algebraic representations of the infinite phylon group
The concept of phylon is introduced as a generalisation of derivative strings, differential strings and new tensors. The behaviour of phyla under change of coordinates is given by finite-dimensional algebraic ...
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Multiple phases and return to equilibrium
This paper considers the problem of return to equilibrium for perturbations of the dynamics of the one-sided and two-sidedXY-models with external field. We find that, in the presence of multiple ground states, re...