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    EAST-Syndrom

    Die Erforschung seltener Erkrankungen ermöglicht häufig entscheidende Erkenntnisse über die Pathophysiologie des Menschen. Kürzlich haben wir ein neues Krankheitsbild bei Kindern beschrieben, welches mit einem...

    Dr. D. Böckenhauer, H. Stanescu, S. Bandulik, M. Reichold, A. Zdebik in Der Nephrologe (2011)

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    The role of KCNQ1/KCNE1 K+ channels in intestine and pancreas: lessons from the KCNE1 knockout mouse

    KCNE1 (IsK, minK) co-assembles with KCNQ1 (KvLQT1) to form voltage-dependent K+ channels. Both KCNQ1 and KCNE1 are expressed in epithelial cells of gut and exocrine pancreas. We examined the role of KCNQ1/KCNE1 ...

    R. Warth, M. Garcia Alzamora, J. Kim, A. Zdebik, R. Nitschke, M. Bleich in Pflügers Archiv (2002)

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    Chloride channels in the luminal membrane of rat pancreatic acini

     Pancreatic acini secrete Na+, Cland H2O in response to secretagogues such as acetylcholine. Clchannels in the luminal membrane are a prerequisite for this secretion. The properties of the corresponding conduct...

    A. Zdebik, M. J. Hug, R. Greger in Pflügers Archiv (1997)

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    Whole-cell conductive properties of rat pancreatic acini

    Acetylcholine-controlled exocrine secretion by pancreatic acini has been explained by two hypotheses. One suggests that NaCl secretion occurs by secondary active secretion as has been originally described for ...

    M. Slawik, A. Zdebik, M. J. Hug, D. Kerstan, J. Leipziger, R. Greger in Pflügers Archiv (1996)