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Article
Three-Dimensional Structure of the Triple Mutant DiB3-F53L/F74L/L129M of the Fluorescent Complex of Bacterial Lipocalin with a Chromophore
Objective: In the development of biomarker systems for cell biology, Blc lipocalin proved to be a promising scaffold for binding the fluorogen M739. This work presents the results of the molecular dynamics study ...
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Article
Alternative Chromophore Binding Sites in Noncovalent Fluorescent Complexes of Bacterial Lipocalin
The three-dimensional structure of DiB3, a fluorescent noncovalent complex of a genetically engineered variant of the bacterial protein lipocalin Blc with the synthetic GFP-like chromophore M739, was determine...
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Article
SOD1 gene mutations in patients with amyotrophic lateral sclerosis: Potential of method of molecular modeling
Molecular modeling is a promising method for assessing protein structures that is capable of presenting an energetically beneficial protein conformation with atomic precision. This method is of great importanc...