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Article
Analysis of the State of a Geomat Filled with Crushed Stone with a Bitumen Polymer Binder Several Years After Production
This study compares samples of erosion resistant coatings made of geomat filled with crushed stone with bituminous and bitumen-polymer binders. The comparison was made several years after the production of the...
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Article
Scheduling Problem for Call Center Operators
The paper is devoted to solving the problem of scheduling the work of the call center staff. A model of integer linear programming is formulated, the problem is shown to be NP-hard, and a genetic algorithm is...
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Article
Comparison of Roughness Coefficients of Geomats with Crushed Stone and Bitumen-Polymer Binder with Similar Coatings
The roughness coefficients of erosion-control coatings based on geomats are studied. The roughness coefficients were calculated following an analysis of relevant publications. The process of determining the ro...
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Article
Modularity in Biological Evolution and Evolutionary Computation
The basic principles of selectionism were transferred in a simplified form from population genetics to the field of evolutionary computation in order to solve applied problems of optimization and adaptation. C...
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Article
The Role of Mutant RNA in the Pathogenesis of Huntington’s Disease and Other Polyglutamine Diseases
Polyglutamine diseases are rare, inherited neurodegenerative pathologies that arise as a result of expansion of trinucleotide CAG repeats in the coding segment of certain genes. This expansion leads to the app...
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Article
At Home among Strangers: Is It Possible to Create Hypoimmunogenic Pluripotent Stem Cell Lines?
Human pluripotent stem cells, which include embryonic stem cells and induced pluripotent cells (iPSCs), are capable of unlimited division and differentiation into all cells of the body. These cells are conside...
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Article
“Necessity Is the Mother of Invention” or Inexpensive, Reliable, and Reproducible Protocol for Generating Organoids
Organoids are three-dimensional (3D) cell cultures that replicate some of the key features of morphology, spatial architecture, and functions of a particular organ. Organoids can be generated from both adult a...
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Article
On computational complexity of the electric power flow optimization problem in market environment
Under consideration is the electric power flow optimization problem for an electric power system which typically arises in calculation of electrical power auctions in the “day-ahead” and balancing markets. It ...
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Article
Analysis of a multicriterial buffer capacity optimization problem for a production line
We consider a multicriterial optimization problem for volumes of buffers in a production line. We assume that the line has a series-parallel structure, and during its operation equipment stops occur due to fai...
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Article
On the complexity and approximability of some Euclidean optimal summing problems
The complexity status of several well-known discrete optimization problems with the direction of optimization switching from maximum to minimum is analyzed. The task is to find a subset of a finite set of Eucl...
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Article
On the complexity of some Euclidean optimal summing problems
The complexity status of several discrete optimization problems concerning the search for a subset of a finite set of Euclidean points (vectors) is analyzed. In the considered problems, the aim is to minimize ...
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Article
Trading hubs construction in electricity markets using evolutionary algorithms
The trading hubs construction problem for electricity markets under locational marginal prices is considered. Given historical prices for all nodes of the electricity grid and for all market participants over ...
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Article
Isolation of germ-cell precursors from human ovary tissue
This article describes the isolation of germ-cell precursors from human ovary tissues collected during various gynecological operations. Two cell cultures were established from tunica albuginea tissue. These c...
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Article
Reaction of 6-arylidene-2,2-dimethylcyclohexanones with phenylhydrazine. Molecular and crystal structures of 3-(4-halophenyl)-1-phenyl-4,5,6,7-tetrahydro-(2H)-indazoles
The previously unknown 3-(4-chlorophenyl)-7,7-dimethyl-2-phenyl-3,3a,4,5,6,7-hexahydroindazole 6a and (4-halophenyl)-7,7-dimethyl-1-phenyl-4,5,6,7-tetrahydroindazoles 7a,b were synthesized by the reaction of 6-ar...
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Article
A genetic algorithm with tournament selection as a local search method
Some sufficient conditions are found under which the generational genetic algorithm with tournament selection first visits a local optimum in polynomially bounded time on average. These conditions are satisfie...
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Article
Mouse Hepatocytes Retain the Expression of the Main Differentiation Markers during Culturing on Collagen-Chitosan Matrices
Mouse hepatocytes cultured on artificial 3D collagen-chitosan biopolymer matrices retained the expression of hepatocyte markers for 14 days.
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Article
Some fully polynomial time randomized approximation scheme based on an evolutionary algorithm
Considering the class of discrete optimization problems that satisfy the Woeginger conditions of existence of a fully polynomial-time approximation scheme, we propose a fully polynomial-time randomized approxi...
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Article
Orto-aminoazotoluen induces the expression of the p53 gene in inbred strains of mice susceptible and resistant to hepatocarcinogenesis
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Article
o-Aminoazotoluene suppresses hepatocyte proliferation in inbred mice susceptible to hepatocarcinogenesis
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Article
Derivation of a novel human embryonic stem cell line under serum-free and feeder-free conditions
