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Article
Milk production in pottery. Evidence for various exploited resources used by the first farmers in Central Pyrenees using the morphological, chemical and stable carbon isotopic composition of organic residues from ceramic vessels
From the second part of the 6th millennium BC onwards, pottery manufacture is attested throughout the western Mediterranean. The study of the functional and use of vessels has become a valuable source of infor...
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Article
Open AccessEarly Dalmatian farmers specialized in sheep husbandry
The spread of farming in the central and western Mediterranean took place rapidly, linked to the Impressa Ware. The Impressa Ware originated somewhere in the southern Adriatic and spread westwards across the M...
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Article
Open AccessEssential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse develo** brain
Omega-3 fatty acids (n-3 PUFAs) are essential for the functional maturation of the brain. Westernization of dietary habits in both developed and develo** countries is accompanied by a progressive reduction i...
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Article
Open AccessStem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition
Inhibitors of the mechanistic target of rapamycin (mTOR) are currently used to treat advanced metastatic breast cancer. However, whether an aggressive phenotype is sustained through adaptation or resistance to...
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Article
Extracellular matrix 1 (ECM1) regulates the actin cytoskeletal architecture of aggressive breast cancer cells in part via S100A4 and Rho-family GTPases
ECM1 overexpression is an independent predictor of poor prognosis in primary breast carcinomas, however the mechanisms by which ECM1 affects tumor progression have not been completely elucidated. ECM1 was sile...
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Article
Life-threatening hematochezia from a rectal venous malformation successfully treated with microfoam sclerotherapy: description of a new technique
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Article
Open AccessBreast cancer brain metastases: a review of the literature and a current multidisciplinary management guideline
Breast cancer represents the second most frequent etiology of brain metastasis (BM). It is estimated that 10–30 % of patients with breast cancer are diagnosed with BM. Breast cancer BM are increasing due to th...
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Article
Erratum: Peroxiredoxin 2 specifically regulates the oxidative and metabolic stress response of human metastatic breast cancer cells in lungs
Correction to: Oncogene (2012) 31, 000–000; doi:10.1038/onc.2012.93; published online 19 March 2012 Since the publication of the above manuscript, the authors have identified an error in the author list; the n...
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Article
Peroxiredoxin 2 specifically regulates the oxidative and metabolic stress response of human metastatic breast cancer cells in lungs
Little is known about metastatic pathways that are specific to the lung rather than other organs. We previously showed that antioxidant proteins such as peroxiredoxins were specifically upregulated in lung met...
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Article
Ventilator-associated pneumonia with or without toothbrushing: a randomized controlled trial
Certain guidelines for the prevention of ventilator-associated pneumonia (VAP) recommend oral care with chlorhexidine, but none refer to the use of a toothbrush for oral hygiene. The role of toothbrush use has...
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Article
Rifampicin–miconazole-impregnated catheters save cost in jugular venous sites with tracheostomy
Antimicrobial-impregnated catheters are more expensive than standard catheters (S-C). A higher incidence of catheter-related bloodstream infection (CRBSI) has been found in jugular venous access with tracheost...
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Article
Efficiency of rifampicin–miconazole-impregnated catheters in the femoral venous site
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Article
Preliminary characterization of an experimental breast cancer cells brain metastasis mouse model by MRI/MRS
Chemotherapy increases survival in breast cancer patients. Consequently, cerebral metastases have recently become a significant clinical problem, with an incidence of 30–40% among breast carcinoma patients. As...
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Article
An endotracheal tube with a polyurethane cuff and subglottic secretion drainage reduces the incidence of primary and secondary endogenous ventilator-associated pneumonia
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Article
Robustness of activity of Calvin cycle enzymes after high light and low temperature conditions in Antarctic vascular plants
Only two vascular plants have naturally colonized the Maritime Antarctic: Colobanthus quitensis and Deschampsia antarctica. We propose that one of the reasons of their success in this environment is the robustnes...
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Article
Closed endotracheal suction system without periodic change versus open endotracheal system
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Article
Brain steroidogenesis: emerging therapeutic strategies to prevent neurodegeneration
Decreasing levels of gonadal steroids with aging are associated to an increase in cognitive, neurological and psychiatric disturbances. Estradiol is neuroprotective in animal models of neurodegeneration. Howev...
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Article
Ventilator-associated pneumonia with a closed versus an open endotracheal suction system
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Article
Periodic change of ventilator circuits: an unnecessary cost
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Chapter and Conference Paper
Skip** Fisher’s Criterion
A new version of Fisher’s discriminant analysis (FDA) is introduced in this paper. Our algorithm searches also for a reduced space in which patterns can be discriminated. However, no intermediate class separab...
