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Article
Gravastars in f(G, T2) Gravity
The focus of our work is the analysis of a specific celestial structure known as a gravastar in the background of \(f(G, {\textbf{T}}^{2})\) ...
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Article
Open AccessAnalytical solutions of spherical structures with relativistic corrections
This paper analyzes the characteristic of a non-static sphere along with anisotropic fluid distribution in the background of modified $$f(\mat...
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Chapter and Conference Paper
Performance of Jointed S&C Bearers
Long bearers are used at switches and crossings (S&C) to maintain the gauge and prevent relative lateral movement between the rails for all possible routes a train may take. Traditionally, these bearers are fo...
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Article
Phosphonium-based hydrophobic ionic liquids with fluorous anions for biodiesel production from waste cooking oil
In this work, ionic liquids (ILs) containing the phosphonium cation and four different types of fluorous anions were synthesized and characterized with nuclear magnetic resonance spectroscopy, Fourier-transfo...
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Article
Open AccessFirst-in-class oral small molecule inhibitor of the tyrosine kinase ROR1 (KAN0439834) induced significant apoptosis of chronic lymphocytic leukemia cells
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Article
Identification of QTLs on chromosome 1B for grain quality traits in bread wheat (Triticum aestivum L.)
The present study was designed considering the importance of grain quality traits, genetic diversity and marker-trait association analysis in wheat. A significant amount of genetic diversity was found for vari...
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Article
Historical and experimental evidence for enhanced concentration of artemesinin, a global anti-malarial treatment, with recent and projected increases in atmospheric carbon dioxide
Although the role of rising atmospheric carbon dioxide concentration [CO2] on plant growth and fecundity is widely acknowledged as important within the scientific community; less research is available regarding t...
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Article
Open AccessRegulation of the pentose phosphate pathway by an androgen receptor–mTOR-mediated mechanism and its role in prostate cancer cell growth
Cancer cells display an increased demand for glucose. Therefore, identifying the specific aspects of glucose metabolism that are involved in the pathogenesis of cancer may uncover novel therapeutic nodes. Rece...
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Article
Monoclonal antibodies against ROR1 induce apoptosis of chronic lymphocytic leukemia (CLL) cells
ROR1 is a receptor tyrosine kinase (RTK) recently identified to be overexpressed at the gene and protein levels in chronic lymphocytic leukemia (CLL). Monoclonal antibodies (MAbs) against RTKs have been succes...
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Article
Genetic diversity in basmati rice (Oryza sativa L.) germplasm as revealed by microsatellite (SSR) markers
Genetic diversity among rice genotypes, including 15 indica basmati advance lines and 5 basmati improved varieties were investigated by 28 SSR markers including one indel marker. The SSRs covered all the 12 ch...
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Article
Genetic Analysis of Physio-morphological Traits in Bread Wheat (Triticum aestivum L.) under Water Stress Conditions
A diallel cross involving six wheat varieties, namely Sehar 06, Punjab 96, GA 2002, Barani 83, Kohistan 97 and Chakwal 86 was carried out to determine the mode of gene action for some physio-morphological trai...
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Article
Prototype development and preclinical immunogenicity analysis of a novel minimally invasive electroporation device
The magnitude of the immune response to a DNA vaccine depends on three criteria—the optimized vector design, the use of a suitable adjuvant and the successful delivery and subsequent expression of the plasmid ...
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Chapter
Carbohydrate Receptors of Bacterial Adhesins: Implications and Reflections
Bacteria entering a host depend on adhesins to achieve colonization. Adhesins are bacterial surface structures mediating binding to host surficial areas. Most adhesins are composed of one or several proteins. ...
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Article
DNA immunization using constant-current electroporation affords long-term protection from autochthonous mammary carcinomas in cancer-prone transgenic mice
A recently developed, adaptive constant-current electroporation technique was used to immunize mice with an intramuscular injection of plasmid coding for the extracellular and transmembrane domains of the prod...
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Article
Functional analysis of the minor subunits of S fimbrial adhesin (SfaI) in pathogenic Escherichia coli
S fimbrial adhesins I and II (SfaI and II), produced by extraintestinal Escherichia coli pathogens that cause urinary tract infections (UTI) and newborn meningitis (NBM), respectively, mediate bacterial adherenc...
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Chapter and Conference Paper
Patients infected with high-hazard viruses: scientific basis for infection control
Most of the viral hemorrhagic fevers (VHFs) are caused by viruses that are handled in high containment laboratories in Europe and the United States because of their high pathogenicity and their aerosol infecti...
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Article
Patients with and without oral malignancy in Pakistan. A dental elective report
As part of the undergraduate course, final year students are encouraged to undertake a 2 week elective study, in order to gain a deeper insight into a chosen branch of dentistry. Since we both had an interest ...
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Article
Shear measurement using strain gages under large deformation and rotation
The measurement of shear strain under finite deformation and large rotation by using electrical-resistance metallic foil strain gages is studied both analytically and experimentally. Equations for calculating ...
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Article
On the use of electrical-resistance metallic foil strain gages for measuring large dynamic plastic deformation
The use of electrical-resistance metallic foil strain gages for measuring large plastic strain in dynamic experiments in studied. The maximum nominal strains obtained in this investigation are 35 percent in co...
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Article
Evaluation of the stability of discharge workings