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Article
PERSISTENCE OF IMMUNOLOGIC FACTORS FROM HUMAN MILK IN THE INTESTINAL TRACT OF VERY LOW BIRTH WEIGHT INFANTS
The use of banked human milk for premature infants is frequently based on the potential importance of its immunologic components. We therefore examined the persistence of some immunologic factors from human mi...
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Article
Evidence for involvement of arachidonic acid in the teratogenic action of glucocorticoids
In addition to inhibiting shelf elevation glucocorticoids have been shown by us to inhibit breakdown of the medial edge epithelium of fetal palatal shelves from steroid-sensitive mouse strains in vivo and in a...
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Article
Biochemical mechanism of corticoid-induced cleft palate in rats linked to anti-inflammatory action
Glucocorticoids produce cleft palate in offspring of rodents in direct relation to their anti-inflammatory potency. Recently,the anti-inflammatory action of glucocorticoids has been shown to be inhibition of a...
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Article
LYMPHOCYTE MOTILITY IN CHRONIC LYMPHOCYTIC LEUKEMIA(CLL)AND X-UNKED HYPO-M-GLOBULINEMIA
We have found that circulating human T lymphocytes are motile, whereas unstimulated B lymphocytes are not (RES, J.Reticuloendothel.Soc.20:331, 1976). Since motility is a functional morphologic marker of normal...
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Article
EFFECT OF RBC TRANSFUSIONS ON ADENOSINE DEAMINASE(ADA) DEFICIENT SEVERE COMBINED IMMUNODEFICIENCY(SCID)
Previous work suggests that the immunological defect in ADA deficient SCID is mediated by increased lymphocyte nucleotides including ATP and cAMP. We attempted to improve this tmmunological deficit in a 10-mon...
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Article
QUANTITATIVE IMMUNOSORBE NT ASSAY FOR SlgA
Studies of the secretory immune system have been hampered by the lack of an assay to specifically measure SIgA in secretions which also contain serum IgA and free secretory componet (FSC). We have developed an...
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Article
The Cells of Human Colostrum II. Synthesis of IgA and β1c
Extract: The production of IgG, IgA, IgM, β1c, and the secretory piece (SP) by the cells of human colostrum was investigated by radioimmunoelectrophoresis. The synthesis of IgA and β1c by the cells was demonst...
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Article
The Cells of Human Colostrum. I. In Vitro Studies of Morphology and Functions
Extract: The morphology and certain functions of human colostral cells were studied in vitro. Colostrum from 60 human females contained neutrophils, small lymphocytes, macrophages and occasional epithelial cells....