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    Article

    Phage Antibodies for Kanamycin Detection

    Recombinant antibodies specific to kanamycin were obtained using a sheep display library of scFv fragments (Griffin.1) and the possibility of their use for the determination of kanamycin by dot-immunoassay was...

    O. I. Guliy, S. S. Evstigneeva, S. A. Staroverov in Applied Biochemistry and Microbiology (2023)

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    Polymeric Micelles for Targeted Drug Delivery System

    Targeted drug transport is becoming more and more popular for increasing the efficiency of interactions between a drug and a target. This method allows the drug concentration to be increased at a desired site ...

    O. I. Guliy, S. A. Staroverov, A. S. Fomin in Applied Biochemistry and Microbiology (2022)

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    Article

    Phage Antibodies as Bioreceptors for Ampicillin Detection

    Ampicillin-specific antibodies were obtained using a sheep display library of scFv fragments (Griffin.1, UK). Ampicillin was determined by dot-immunoassay with biospecific interaction of selected recombinant a...

    O. I. Guliy, A. K. M. Alsowaidi, A. S. Fomin in Applied Biochemistry and Microbiology (2022)

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    Cytotoxicity of Flavonoid-Containing Plant Extracts toward the CHO Cell Line: a Comparative Study

    The effects that sandy everlasting, purple corn, and hedge hyssop extracts have on the viability and metabolic activity of monolayer cell cultures of the Chinese hamster ovary (CHO) cell line are studied using...

    M. N. Kurchatova, A. S. Fomin, A. A. Shirokov, N. A. Durnova in Cell and Tissue Biology (2022)

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    Immunodetection of bacteriophages by a piezoelectric resonator with lateral electric field

    It has been demonstrated that electroacoustic analysis with polyclonal antibodies can be used for bacteriophage detection. The frequency dependences of the real and imaginary parts of electrical impedance of a...

    O. I. Guliy, B. D. Zaitsev, A. M. Shikhabudinov in Applied Biochemistry and Microbiology (2016)

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    Penetration of the peptide lactaptin into human cancer cells

    Lactaptin, a human milk protein with a molecular weight of 8.6 kDa, is a fragment of human ?casein, which has cytotoxic activity toward mammalian cancer cells in vitro. RL2 is a recombinant analogue of lactapt...

    O. A. Chinak, A. S. Fomin, A. A. Nushtaeva in Russian Journal of Bioorganic Chemistry (2016)

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    Article

    Analysis of biochemical markers of MCF-7 cell apoptosis induced by a recombinant analogue of lactaptin

    Earlier, a pro-apoptotic peptide lactaptin was isolated from human milk and characterized and its recombinant analogue RL2 was generated. Both peptides were demonstrated to be capable of apoptotic cell death i...

    A. S. Fomin, O. A. Koval, D. V. Semenov in Russian Journal of Bioorganic Chemistry (2012)