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  1. No Access

    Article

    A New Human Uveal Melanoma Cell Line: Melanin Production and Molecular Markers for Targeted Therapy

    A new human uveal melanoma (UM) cell line uMel1 was established by mechanical disintegration of a tumor fragment. uMel1 cells had a stellate dendrite-like shape, contained a lot of brown melanin pigment, and h...

    M. V. Zhilnikova, D. D. Novak… in Biochemistry (Moscow), Supplement Series B… (2023)

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    Breast Cancer Cells in 3D Model Alters Their Sensitivity to Hormonal and Growth Factors

    The purpose of this work was to study the formation and growth of mono- (3D) and heterogeneous (3D-2) spheroids composed of stromal and tumor cells that mimic three types of breast cancer: ER+/PR+, HER2+, and ER-

    A. A. Nushtaeva, M. M. Savinkova, M. S. Ermakov, M. E. Varlamov… in Cell and Tissue Biology (2022)

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    Tumor Specific Peptides Selected for Targeted Delivery of Therapeutic Agents to Glioma Human Cells

    Brain tumors are among the most intractable types of malignant neoplasms. Despite advances in the treatment of cancer, in particular, the development of new approaches in surgery, radiotherapy and chemotherapy...

    A. A. Voitova, M. D. Dmitrieva, M. A. Dymova… in Russian Journal of Bioorganic Chemistry (2019)

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    Article

    Penetration of the peptide lactaptin into human cancer cells

    Lactaptin, a human milk protein with a molecular weight of 8.6 kDa, is a fragment of human ?casein, which has cytotoxic activity toward mammalian cancer cells in vitro. RL2 is a recombinant analogue of lactapt...

    O. A. Chinak, A. S. Fomin, A. A. Nushtaeva… in Russian Journal of Bioorganic Chemistry (2016)