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  1. No Access

    Article

    Long-term impact of temozolomide on 1p/19q-codeleted low-grade glioma growth kinetics

    Although upfront temozolomide (TMZ) has been widely-used to treat 1p/19q-codeleted diffuse low-grade gliomas (LGG), its long-term impact on the growth kinetics of these tumors has not been determined. Based on...

    C. Izquierdo, A. Alentorn, A. Idbaih, M. Simó, G. Kaloshi… in Journal of Neuro-Oncology (2018)

  2. No Access

    Article

    Prevalence of hepatitis B virus in primary central nervous system lymphoma

    G. Faivre, V. Thibault, M. L. Tanguy, V. Leblond, S. Choquet… in Journal of Neuro-Oncology (2015)

  3. No Access

    Article

    Avancées dans les tumeurs cérébrales primitives malignes de l’adulte : quels patients transférer en réanimation médicale?

    Les progrès thérapeutiques réalisés ces dernières années ont permis d’améliorer de manière significative le pronostic et la qualité de vie des patients souffrant de tumeurs cérébrales primitives malignes (TCPM...

    A. Alentorn, N. Weiss, J. -Y. Delattre, A. Idbaih in Réanimation (2015)

  4. Article

    Open Access

    TERT promoter mutations in gliomas, genetic associations and clinico-pathological correlations

    The role of telomerase reverse transcriptase (TERT) in gliomagenesis has been recently further strengthened by the frequent occurrence of TERT promoter mutations (TERTp-mut) in gliomas and evidence that the TERT ...

    M Labussière, A L Di Stefano, V Gleize, B Boisselier, M Giry… in British Journal of Cancer (2014)

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  5. No Access

    Article

    Glioma tumor grade correlates with parkin depletion in mutant p53-linked tumors and results from loss of function of p53 transcriptional activity

    Gliomas represent the most frequent form of primary brain tumors in adults, the prognosis of which remains extremely poor. Inactivating mutations on the tumor suppressor TP53 were proposed as a key etiological tr...

    J Viotti, E Duplan, C Caillava, J Condat, T Goiran, C Giordano, Y Marie… in Oncogene (2014)

  6. No Access

    Article

    Ongoing and prolonged response in adult low-grade gliomas treated with radiotherapy

    The aim of the present study was to evaluate the impact of first-line radiotherapy on low-grade gliomas (LGGs) growth kinetics. The mean tumor diameter (MTD) of 39 LGGs was retrospectively measured on serial ...

    F. Ducray, G. Kaloshi, C. Houillier, A. Idbaih, B. Ribba… in Journal of Neuro-Oncology (2013)

  7. Article

    Open Access

    Low penetrance susceptibility to glioma is caused by the TP53 variant rs78378222

    Most of the heritable risk of glioma is presently unaccounted for by mutations in known genes. In addition to rare inactivating germline mutations in TP53 causing glioma in the context of the Li-Fraumeni syndrome...

    V Enciso-Mora, F J Hosking, A L Di Stefano, D Zelenika… in British Journal of Cancer (2013)

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  8. No Access

    Article

    MRI features of neurodegenerative Langerhans cell histiocytosis

    CNS complications of LCH include “space occupying” lesions corresponding to histiocytic granulomas and “neurodegenerative” presentation (ND-LCH) characterized by a progressive cerebellar ataxia. Studies analyz...

    N. Martin-Duverneuil, A. Idbaih, K. Hoang-Xuan, J. Donadieu… in European Radiology (2006)