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  1. No Access

    Article

    CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to γ-secretase inhibitors

    Activating mutations in NOTCH1 are present in over 50% of human T-cell lymphoblastic leukemia (T-ALL) samples and inhibition of NOTCH1 signaling with γ-secretase inhibitors (GSI) has emerged as a potential therap...

    T Palomero, K C Barnes, P J Real, J L Glade Bender, M L Sulis, V V Murty… in Leukemia (2006)

  2. No Access

    Article

    Tolerization of dendritic cells by TS cells: the crucial role of inhibitory receptors ILT3 and ILT4

    Immunoglobulin-like transcript 3 (ILT3) and ILT4 belong to a family of inhibitory receptors expressed by human monocytes and dendritic cells. We show here that CD8+CD28− alloantigen-specific T suppressor (TS) cel...

    C. C. Chang, R Ciubotariu, J. S. Manavalan, J. Yuan, A. I. Colovai… in Nature Immunology (2002)