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Article
Open AccessEffect of empagliflozin on ectopic fat stores and myocardial energetics in type 2 diabetes: the EMPACEF study
Empagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor that has demonstrated cardiovascular and renal protection in patients with type 2 diabetes (T2D). We hypothesized that empaglifozin (EMPA) co...
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Article
Pioglitazone in adult rats reverses immediate postnatal overfeeding-induced metabolic, hormonal, and inflammatory alterations
Immediate postnatal overfeeding in rats, obtained by reducing the litter size, results in early-onset obesity. Such experimental paradigm programs overweight, insulin resistance, dyslipidemia, increased adipos...
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Article
Open AccessComparison of the gut microbiota of people in France and Saudi Arabia
The gut microbiota contributes to energy acquisition from food, and changes in the gut microbiome are associated with obesity. The eating habits of Saudis are much different than those of Europeans, and our ob...
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Chapter
Circulating Blood Glucose and Hypothalamic-Pituitary Secretion
Normally glucose accounts for more than 90% of the metabolic fuel of the brain (1). A constant supply and utilization of glucose is essential for normal cerebral metabolism since brain carbohydrate stores are ...
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Chapter
Differences in the Effects of Acute and Chronic Administration of Dexfenfluramine on Cortisol and Prolactin Secretion
The involvement of serotonin on neuroendocrine regulation has been substantiated by much experimental data. Indeed, serotonin has been shown to play a role in the regulation of pituitary hormones that display ...
