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Open AccessStructured Assessment for Prospective Identification of Safety Signals in Electronic Medical Records: Evaluation in the Health Improvement Network
Pharmacovigilance signal detection largely relies on individual case reports, but longitudinal health data are being explored as complementary information sources. Research to date has focused on the ability o...
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Article
Ascertainment of acute liver injury in two European primary care databases
The purpose of this study was to ascertain acute liver injury (ALI) in primary care databases using different computer algorithms. The aim of this investigation was to study and compare the incidence of ALI in...
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Article
Incidence Rates and Trends of Hip/Femur Fractures in Five European Countries: Comparison Using E-Healthcare Records Databases
Hip fractures represent a major public health challenge worldwide. Multinational studies using a common methodology are scarce. We aimed to estimate the incidence rates (IRs) and trends of hip/femur fractures ...
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ABSTRACTS: ISoP Annual Conference ‘Joining Forces for Managing Risks’ Liège, Belgium 11–13 October, 2006
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Data-mining analyses of pharmacovigilance signals in relation to relevant comparison drugs
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Article
A Bayesian neural network method for adverse drug reaction signal generation
Objective: The database of adverse drug reactions (ADRs) held by the Uppsala Monitoring Centre on behalf of the 47 countries of the World Health Organization (WHO) Collaborating Programm...
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Angiogenesis in Atherosclerosis: Possible Roles for Vascular Endothelial Cell Growth Factor, Endothelial Cell Stimulating Angiogenesis Factor and Soluble E-Selectin
Endothelial cell injury is believed to be an important early step in the pathogenesis of atherosclerosis, and there is evidence of endothelial cell dysfunction in the risk factors for this disease[1–4]. It fol...