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  1. No Access

    Article

    Cystathionine-γ-lyase gene silencing with siRNA in monocytes/macrophages attenuates inflammation in cecal ligation and puncture-induced sepsis in the mouse

    Hydrogen sulphide is an endogenous inflammatory mediator produced by cystathionine-γ-lyase (CSE) in macrophages. To determine the role of H2S and macrophages in sepsis, we used small interference RNA (siRNA) to t...

    A Badiei, S T Chambers, R R Gaddam, M Bhatia in Journal of Biosciences (2016)

  2. No Access

    Article

    Cystathionine-gamma-lyase gene silencing with siRNA in monocytes/macrophages protects mice against acute pancreatitis

    Hydrogen sulphide (H2S) is an endogenous inflammatory mediator produced by cystathionine-γ-lyase (CSE) in monocytes/macrophages. To determine the role of H2S and macrophages in inflammation, we used small interfe...

    A. Badiei, S. T. Chambers, R. R. Gaddam… in Applied Microbiology and Biotechnology (2016)