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Article
In Vitro Effect of Fucose-Specific Lectins on Rat Erythrocyte Membranes under Normal Conditions and during Toxic Stress
We studied the effect of various fucose-specific lectins on lipid peroxidation in rat erythrocyte membranes under normal conditions and during exposure to the toxic agent. Under normal conditions parameters of...
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Article
Mutagenic Effect of Gold Nanoparticles in the Micronucleus Assay
Mutagenic activity of gold nanoparticles of different sizes were studied by micronucleus assay. Karyological analysis was performed and the count of micronucleoli in interphase bone marrow polychromatic erythr...
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Article
Synthesis of magnetite hydrosols and assessment of their impact on living systems at the cellular and tissue levels using MRI and morphological investigation
MRI and morphological investigations into internal organ tissues and tumors in rats with liver cancer PC-1 under the intraperitoneal administration of magnetite hydrosols have been performed. The absence of an...
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Article
Calcium carbonate microparticles containing a photosensitizer photosens: Preparation, ultrasound stimulated dye release, and in vivo application
Calcium carbonate microparticles with a size of 0.9 ± 0.2 μm containing a photosensitizer Photosens in a concentration of 2.0 ± 0.2 wt % were prepared by ultrasound-stimulated coprecipitation (20 kHz, 1W/cm2). It...
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Article
Cancer Cell Damage at Laser-Induced Plasmon-Resonant Photothermal Treatment of Transplanted Liver Tumor
Here, we report the morphological investigation of gold nanorod (GNR)-mediated photothermal changes in transplanted liver tumors PC-1 and discuss photothermal induced therapeutic pathways of cancer cell damage...
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Article
Polyphenolic compounds of a new biologically active extract from immortelle sandy flowers (Helichrysum arenarium (L.) Moench.)
The chemical composition of a new bioactive extract from immortelle sandy (Helichrysum arenarium (L.) Moench.) was investigated. Naringin, its soluble aggregate, prunin, quercetin, apigenin, naringenin, apigenin ...
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Article
Plasmonic Photothermal Therapy of Transplanted Tumors in Rats at Multiple Intravenous Injection of Gold Nanorods
The aim of this study was to evaluate the morphological changes in tumor tissue in rats with transplanted liver cancer PC-1 after repeated intravenous (IV) administration of gold nanorods (GNRs) and plasmonic ...
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Article
Advantages and Possibilities of Fluorescence-Based Methods for the Visualization of Apoptosis and Autophagy in Human Tumor Cells in vitro
The possibilities of using fluorescence-based analytical methods and their advantages for visualization and identification of the type of programmed cell death in human tumor cells exposed to flavonoids have b...
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Article
A Complex Study of the Peculiarities of Blood Serum Absorption of Rats with Experimental Liver Cancer
Terahertz time-domain spectroscopy (THz-TDS) in the 0.05–1.0 THz frequency range was used to study the blood serum of rats in the dynamics of experimental liver cancer. It was shown that the THz transmission s...
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Article
The Influence of Long-Term Peroral Administration of Gold Nanoparticles with Various Sizes on the Liver, Spleen, and Lymph Nodes of Laboratory Rats and Their Progeny
The influence of long-term peroral injection of gold nanoparticles with various sizes on the liver, spleen, and lymph nodes of adult laboratory rats and their progeny was studied. The morphometric analysis was...
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Article
Efficiency of Plasmonic Photothermal Therapy of Experimental Tumors
The purpose of this study was to investigate the prognostic factors of plasmonic photothermal therapy (PPT) efficiency in rats with transplanted liver cancer on the basis of assessment of the degree of tumor v...
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Article
Comparative Spectroscopic and HPLC Analyses of Phenolic Compounds in Extracts of Anthocyanin Maize Purple Saratov Variety Grown Under Various Wetting Conditions
The quercetin content in aqueous EtOH extracts of covering leaves of anthocyanin Purple Saratov diploid variety of Zea mays L. grown under dry conditions reached 39.36 ± 0.41 mg/100 g of dry extract and significa...
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Article
Study of Blood Serum in Rats with Transplanted Cholangiocarcinoma Using Raman Spectroscopy
Serum samples of healthy rats and rats with inoculated tumors on days 14 and 28 after transplantation of cholangiocarcinoma cells were analyzed using Raman spectroscopy (RS). It was shown that the intensity of...
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Article
Assessment by the Fluorescence Imaging Methods of the Antitumor Efficacy and Apoptotic Activity of Biologically Active Additives Containing Resveratrol, Indole-3-Carbinol, and Cordycepin in Human Renal Carcinoma Cells
The efficacy of antitumor efficacy and apoptosis induction in A498 human renal cell carcinoma observed when applying extracts of cruciferous herbal material (indole-3-carbinol), Chinese mushroom (cordycepin), ...
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Article
Influence of Immersion Agents on Optical Parameters of Bio-Tissues During Laser Photothermal Therapy of Tumor: Pilot Study
Combined use of an immersion agent with low-intensity laser irradiation for optical clearing of skin before plasmon photothermal therapy (PPTT) procedure is offered. Pilot study results of influence of the imm...
