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Erratum: Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index
Correction to: Molecular Psychiatry advance online publication, 17 May 2016; doi:10.1038/mp.2016.71 Following the online publication of this paper, the first author noticed a mistake in Table 1. The corrected ...
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Article
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index
The maintenance of normal body weight is disrupted in patients with anorexia nervosa (AN) for prolonged periods of time. Prior to the onset of AN, premorbid body mass index (BMI) spans the entire range from un...
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Dysregulation of soluble epoxide hydrolase and lipidomic profiles in anorexia nervosa
Individuals with anorexia nervosa (AN) restrict eating and become emaciated. They tend to have an aversion to foods rich in fat. Because epoxide hydrolase 2 (EPHX2) was identified as a novel AN susceptibility gen...
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Article
Open AccessEvidence for the role of EP HX2 gene variants in anorexia nervosa
Anorexia nervosa (AN) and related eating disorders are complex, multifactorial neuropsychiatric conditions with likely rare and common genetic and environmental determinants. To identify genetic variants assoc...
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Article
Gender-stratified gene and gene–treatment interactions in smoking cessation
We conducted gender-stratified analyses on a systems-based candidate gene study of 53 regions involved in nicotinic response and the brain—reward pathway in two randomized clinical trials of smoking cessation ...
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Varenicline for smoking cessation: nausea severity and variation in nicotinic receptor genes
This study evaluated association between common and rare sequence variants in 10 nicotinic acetylcholine receptor subunit genes and the severity of nausea 21 days after initiating the standard, Food and Drug A...
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Open AccessGenome-wide meta-analyses of smoking behaviors in African Americans
The identification and exploration of genetic loci that influence smoking behaviors have been conducted primarily in populations of the European ancestry. Here we report results of the first genome-wide associ...
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Open AccessEpstein–Barr virus microRNAs and lung cancer
We conducted the first analysis of viral microRNAs (miRNAs) in lung cancer, with a focus on Epstein–Barr virus (EBV).
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Open AccessInherited polymorphisms in the RNA-mediated interference machinery affect microRNA expression and lung cancer survival
MicroRNAs (miRs) have an important role in lung carcinogenesis and progression. Single-nucleotide polymorphisms (SNPs) in genes involved in miR biogenesis may affect miR expression in lung tissue and be associ...
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Candidate genes for anorexia nervosa in the 1p33–36 linkage region: serotonin 1D and delta opioid receptor loci exhibit significant association to anorexia nervosa
Serotonergic and opioidergic neurotransmitter system alterations have been observed in people with eating disorders; the genes for the serotonin 1D receptor (HTR1D) and the opioid delta receptor (OPRD1) are fo...
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Identification of four variants in the tryptophan hydroxylase promoter and association to behavior
One of the most replicated findings in biological psychiatry is the observation of lower 5-hydroxyindoleacetic acid concentrations, the major metabolite of serotonin, in the brain and cerebrospinal fluid of su...
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μ opioid receptor gene variants: lack of association with alcohol dependence
The μ opioid receptor is implicated in the reward, tolerance and withdrawal effects of alcohol and other drugs of abuse.1,2 This hypothesis is supported by the effects of alcohol on beta-endorphin release,3 of μo...
