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  1. No Access

    Article

    −7/7q− syndrome in myeloid-lineage hematopoietic malignancies: attempts to understand this complex disease entity

    The recurrence of chromosomal abnormalities in a specific subtype of cancer strongly suggests that dysregulated gene expression in the corresponding region has a critical role in disease pathogenesis. −7/7q−, ...

    H Honda, A Nagamachi, T Inaba in Oncogene (2015)

  2. No Access

    Article

    SETBP1 mutations drive leukemic transformation in ASXL1-mutated MDS

    Mutations in ASXL1 are frequent in patients with myelodysplastic syndrome (MDS) and are associated with adverse survival, yet the molecular pathogenesis of ASXL1 mutations (ASXL1-MT) is not fully understood. Rece...

    D Inoue, J Kitaura, H Matsui, H-A Hou, W-C Chou, A Nagamachi, K C Kawabata… in Leukemia (2015)

  3. No Access

    Article

    Identification of Zfp521/ZNF521 as a cooperative gene for E2A-HLF to develop acute B-lineage leukemia

    E2A-hepatic leukemia factor (HLF) is a chimeric protein found in B-lineage acute lymphoblastic leukemia (ALL) with t(17;19). To analyze the leukemogenic process and to create model mice for t(17;19)-positive l...

    N Yamasaki, K Miyazaki, A Nagamachi, R Koller, H Oda, M Miyazaki, T Sasaki… in Oncogene (2010)