5 Result(s)
within
A Maxwell Burroughs
Science, Humanities and Social Sciences, multidisciplinary
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Article
Ribosome collisions induce mRNA cleavage and ribosome rescue in bacteria
Ribosome rescue pathways recycle stalled ribosomes and target problematic mRNAs and aborted proteins for degradation1,2. In bacteria, it remains unclear how rescue pathways distinguish ribosomes stalled in the mi...
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Article
Vms1 and ANKZF1 peptidyl-tRNA hydrolases release nascent chains from stalled ribosomes
Ribosomal surveillance pathways scan for ribosomes that are transiently paused or terminally stalled owing to structural elements in mRNAs or nascent chain sequences1, 2. Some stalls in budding yeast are sensed b...
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Article
An atlas of human long non-coding RNAs with accurate 5′ ends
Long non-coding RNAs (lncRNAs) are largely heterogeneous and functionally uncharacterized. Here, using FANTOM5 cap analysis of gene expression (CAGE) data, we integrate multiple transcript collections to gener...
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Article
An atlas of active enhancers across human cell types and tissues
Enhancers control the correct temporal and cell-type-specific activation of gene expression in multicellular eukaryotes. Knowing their properties, regulatory activity and targets is crucial to understand the r...
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Article
Chromatin-associated RNA interference components contribute to transcriptional regulation in Drosophila
RNA interference (RNAi) is generally associated with post-transcriptional gene silencing, but there is growing evidence that small RNAs and RNAi components also have a role in transcriptional gene silencing in...
