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Article
Regulation of Thiamine (Vitamin B1)-Dependent Metabolism in Mammals by p53
Transcriptional factor p53 is a master regulator of energy metabolism. Energy metabolism strongly depends on thiamine (vitamin B1) and/or its natural derivatives. Thiamine diphosphate (ThDP), which is a major ...
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Article
Open AccessFrom uncertainty to gradually managing and awaiting recovery of a periodic condition- a qualitative study of parents´ experiences of PFAPA syndrome
The prevalence of periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome is unknown. Although an uncommon condition, it is considered to be the most common autoinflammatory dis...
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Article
Open AccessAbsolute quantification reveals the stable transmission of a high copy number variant linked to autoinflammatory disease
Dissecting the role copy number variants (CNVs) play in disease pathogenesis is directly reliant on accurate methods for quantification. The Shar-Pei dog breed is predisposed to a complex autoinflammatory dise...
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Article
Preoperative Nutrition and Postoperative Discomfort in an ERAS Setting: A Randomized Study in Gastric Bypass Surgery
Many patients experience postoperative nausea and vomiting (PONV). Preoperative treatment with carbohydrate solutions seems to improve the course after different types of surgery. This study was undertaken to ...
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Article
Heat kernels on regular graphs and generalized Ihara zeta function formulas
We establish a new formula for the heat kernel on regular trees in terms of classical \(I\) ...
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Article
Open AccessMPO deficiency confers impaired processing of neutrophil reactive oxygen species in a patient with severe CRMO
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Article
Open AccessPediatric chronic non-bacterial osteomyelitis in Goteborg, Sweden
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Article
Open AccessChallenging the opinion that SAPHO syndrome is associated with low intracellular ROS production in neutrophils
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Article
Open AccessLocality and universality of quantum memory effects
The modeling and analysis of the dynamics of complex systems often requires to employ non-Markovian stochastic processes. While there is a clear and well-established mathematical definition for non-Markovianit...
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Article
Open AccessPW03-003 – Altered neutrophil function in PFAPA
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Article
Open AccessP02-025 - Homozygous Q705K sequence variant in NLRP3
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Article
Open AccessP16-02. Induction of systemic HIV-1 specific cellular immune responses by oral exposure in exposed uninfected partner of discordant couples
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Article
Enhanced toxicity of purine nucleoside analogs in cells expressing Drosophila melanogaster nucleoside kinase mutants
The multisubstrate deoxyribonucleoside kinase of Drosophila melanogaster (Dm-dNK) is investigated for possible use as a suicide gene in combined gene/chemotherapy of cancer. The enzyme has broader substrate speci...
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Article
Determination of Ephedrine, Pseudo-Ephedrine and Caffeine in a Dietary Product by Capillary Electrophoresis
This paper reports the determination of caffeine, ephedrine and pseudo-ephedrine in a dietary product by two rapid and simple methods utilising capillary electrophoresis (CE). The solutes were extracted from t...
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Article
Establishment and phenotypic characterization of human U937 cells with inducible P210 BCR/ABL expression reveals upregulation of CEACAM1 (CD66a)
Chronic myeloid leukemia (CML) is characterized by the expression of the P210 BCR/ABL fusion protein. The molecular mechanisms behind this oncogene-mediated hematological disease are, however, not fully unders...
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Chapter and Conference Paper
Technical, partner reports containing method descriptions and concise presentation of important results
In the following 15 chapters, partners provide an overview about methods used and highlight results achieved. For application oriented results, the reader is referred to Chapter IV, while basic approaches and ...
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Chapter and Conference Paper
Summary of work carried out in the main tasks of the UNSI project
In the following 8 chapters, a synthesis of task related work is presented which reflects improvements and enhancements of specific scientific topics that have been tackled in the UNSI project.
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Article
Liquid chromatography method development and optimization by statistical experimental design and chromatogram simulations
A liquid chromatographic method has been optimized by the use of an experimental design and chromatogram simulations. The strategy applied started with a statistical experimental design in which so-calledbeta coe...
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Article
Use of immobilised glucoamylase G2 for separation of enantiomers
The aim of this study was to compare the isolated glucoamylase G2 domain as chiral selector with previously presented data obtained using immobilised native glucoamylase as chiral stationary phase. The glucoam...
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Chapter
Confining and Probing Single Molecules in Synthetic Liposomes
As organisms, we are amazingly complex living laboratories. As we move, breathe, think, and eat, seemingly endless chemical reactions and interactions occur inside us. The test tubes, beakers, and flasks used ...
