49 Result(s)

Article

ESICM LIVES 2016: part three

T. Velasquez, G. Mackey, J. Lusk, U. G. Kyle… in Intensive Care Medicine Experimental (2016)

Article

New simplified criteria for predicting massive transfusion in trauma

T Yumoto, A Iida, E Knaup, N Nosaka, S Morisada, T Hirayama, N Shiba… in Critical Care (2014)

Article

Single nucleotide polymorphisms in the gene encoding Krüppel-like factor 7 are associated with type 2 diabetes

Although genetic susceptibility plays an important role in the pathogenesis of type 2 diabetes, most of the genes that influence susceptibility to type 2 diabetes have yet to be identified. Krüppel-like transc...

A. Kanazawa, Y. Kawamura, A. Sekine, A. Iida, T. Tsunoda, A. Kashiwagi… in Diabetologia (2005)

Article

High-resolution SNP map in the 55-kb region containing the selectin gene family on chromosome 1q24–q25

 Immunoglobulin A nephropathy (IgAN) is the most common form of glomerulonephritis characterized by predominant IgA deposits in glomerular mesangium. By means of a genome-wide case-control association study, w...

A. Iida, Y. Nakamura in Journal of Human Genetics (2003)

Article

Erratum: Functional SNPs in the lymphotoxin-α gene that are associated with susceptibility to myocardial infarction

Nature Genet. 32, 650–654 (2002). Published online 11 November 2002; doi:10.1038/ng1047 A typographical error in the third sentence of the abstract resulted in the P value for the association being incorrectly...

K Ozaki, Y Ohnishi, A Iida, A Sekine, R Yamada, T Tsunoda, H Sato… in Nature Genetics (2003)

Article

Catalog of 668 SNPs detected among 31 genes encoding potential drug targets on the cell surface

 We have been publishing a series of detailed maps of single-nucleotide polymorphisms (SNPs) detected within the genomic loci of 145 genes encoding drug-metabolizing enzymes and transporters. As an addition to...

A. Iida, S. Saito, A. Sekine, C. Mishima, Y. Kitamura… in Journal of Human Genetics (2003)

Article

Catalog of 238 variations among six human genes encoding solute carriers (hSLCs) in the Japanese population

We screened DNAs of 48 Japanese individuals for single-nucleotide polymorphisms (SNPs) in six genes encoding proteins of the solute carrier (SLC) family by direct sequencing of their entire genomic regions ex...

S. Saito, A. Iida, A. Sekine, C. Ogawa, S. Kawauchi… in Journal of Human Genetics (2002)

Article

Catalog of 86 single-nucleotide polymorphisms (SNPs) in three uridine diphosphate glycosyltransferase genes: UGT2A1, UGT2B15, and UGT8

We report here three high-density maps of variations found among 48 Japanese individuals in three uridine diphosphate glycosyltransferase (UGT) genes, UGT2A1, UGT2B15, and UGT8. A total of 86 single-nucleotide p...

A. Iida, S. Saito, A. Sekine, C. Mishima, Y. Kitamura… in Journal of Human Genetics (2002)

Article

906 variations among 27 genes encoding cytochrome P450 (CYP) enzymes and aldehyde dehydrogenases (ALDHs) in the Japanese population

 We screened DNAs from 48 Japanese individuals for single-nucleotide polymorphisms (SNPs) in genes encoding 13 cytochrome P450 (CYP) enzymes and 14 aldehyde dehydrogenases (ALDHs) by directly sequencing their ...

S. Saito, A. Iida, A. Sekine, C. Ogawa, S. Kawauchi… in Journal of Human Genetics (2002)

Article

Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8

 Single-nucleotide polymorphisms (SNPs) at some gene loci are useful as markers of individual risk for adverse drug reactions or susceptibility to complex diseases. We have been focusing on identifying SNPs in...

A. Iida, S. Saito, A. Sekine, C. Mishima, Y. Kitamura… in Journal of Human Genetics (2002)

Article

Identification of 779 genetic variations in eight genes encoding members of the ATP-binding cassette, subfamily C (ABCC/MRP/CFTR)

We screened DNAs from 48 Japanese individuals for single-nucleotide polymorphisms (SNPs) in eight genes encoding the ATP-binding cassette, subfamily C (ABCC/MRP/CFTR), by direct sequencing of their entire genomi...

S. Saito, A. Iida, A. Sekine, Y. Miura, C. Ogawa, S. Kawauchi… in Journal of Human Genetics (2002)

Article

Thirteen single-nucleotide polymorphisms (SNPs) in the alcohol dehydrogenase 4 (ADH4) gene locus

The human alcohol dehydrogenase 4 (ADH4) gene encodes the class II ADH4 pi subunit, which contributes to the metabolization of a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, ...

A. Iida, S. Saito, A. Sekine, K. Kondo, C. Mishima… in Journal of Human Genetics (2002)

Article

Catalog of 77 single-nucleotide polymorphisms (SNPs) in the carbohydrate sulfotransferase 1 (CHST1) and carbohydrate sulfotransferase 3 (CHST3) genes

Individual phenotypes with respect to drug response or toxicity often result from genetic variations that alter drug metabolism. We have been focusing on genomic loci that encode various enzymes and transport...

A. Iida, S. Saito, A. Sekine, C. Mishima, Y. Kitamura… in Journal of Human Genetics (2002)