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Article
35th Annual Meeting of the European Association for the Study of Diabetes
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Article
Targeting central serotonergic neurons with lentiviral vectors based on a transcriptional amplification strategy
Numerous pathological processes have been linked to disorders of the central 5-hydroxytryptamine (5HT) system but the possibility of gene therapy through modulation of 5HT system remained unexplored due to the...
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Article
Open AccessLactate-mediated glia-neuronal signalling in the mammalian brain
Astrocytes produce and release L-lactate as a potential source of energy for neurons. Here we present evidence that L-lactate, independently of its caloric value, serves as an astrocytic signalling molecule in th...
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Article
Correction: Corrigendum: Lactate-mediated glia-neuronal signalling in the mammalian brain
Nature Communications 5: Article number: 3284 (2014); Published: 11 February 2014; Updated: 28 May 2014. While this Article was under consideration, Bozzo et al. published their findings on the inhibitory effe...
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Article
A Role for Astrocytes in Sensing the Brain Microenvironment and Neuro-Metabolic Integration
Astrocytes occupy a strategic position in the brain where they can act as an interface between neurones and blood vessels, and neurones and the cerebro-spinal fluid. This location is ideal for functioning as i...