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Article
Perioperative pain management after scapular tip free flap harvesting for head and neck reconstruction using mini-catheters to inject the local anesthetic
Although functional and esthetic results after the use of a scapular tip free flap (STFF) in head and neck reconstruction, and the related donor-site morbidity, have been extensively described, data regarding ...
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Iliac Crest Free Flap
In 1989, Taylor et al. first described an iliac crest free flap based on the deep circumflex iliac artery (DCIA) and deep circumflex iliac vein (DCIV). Ramasastri et al. showed that the ascending branch of the...
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Article
Pre-operative MRI staging of endometrial cancer in a multicentre cancer network: can we match single centre study results?
To evaluate the staging accuracy of magnetic resonance imaging (MRI) for endometrial cancer in daily practice over a 3-year period at a tertiary referral centre receiving scans from a large number of hospitals...
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Article
DarkSide-20k: A 20 tonne two-phase LAr TPC for direct dark matter detection at LNGS
Building on the successful experience in operating the DarkSide-50 detector, the DarkSide Collaboration is going to construct DarkSide-20k, a direct WIMP search detector using a two-phase Liquid Argon Time Pro...
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Article
Open AccessInefficient skeletal muscle oxidative function flanks impaired motor neuron recruitment in Amyotrophic Lateral Sclerosis during exercise
This study aimed to evaluate muscle oxidative function during exercise in amyotrophic lateral sclerosis patients (pALS) with non-invasive methods in order to assess if determinants of reduced exercise toleranc...
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Open AccessAcute focal brain damage alters mitochondrial dynamics and autophagy in axotomized neurons
Mitochondria are key organelles for the maintenance of life and death of the cell, and their morphology is controlled by continual and balanced fission and fusion dynamics. A balance between these events is ma...
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Different methods for β-cyclodextrin/triclosan complexation as antibacterial treatment of cellulose substrates
Two different production ways of antibacterial cotton fabrics by means of triclosan inclusion into a β-cyclodextrin cavity have been compared. On the one hand, triclosan has been dissolved into an aqueous solu...
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Evaluation of Damages Induced by Ga+-Focused Ion Beam in Piezoelectric Nanostructures
The impact of Ga+-focused ion beam (FIB) about functional properties of continuous and nanostructured piezoelectric thin films of lead zirconate titanate (Pb(ZrxTi1-x)O3) was investigated. A suitable way to fabri...
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Article
A comparison of analytical methods for the quantification of a reactive β-cyclodextrin fixed onto cotton yarns
Cotton yarns bobbins were treated in a water bath with different concentrations of a reactive β-cyclodextrin derivative. To quantify the amount of cyclodextrin fixed on the fiber different analytical methods w...
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Adverse Effects of 2,4-Dichlorophenoxyacetic Acid on Rat Cerebellar Granule Cell Cultures Were Attenuated by Amphetamine
2,4-Dichlorophenoxyacetic acid (2,4-D), a worldwide-used herbicide, has been shown to produce a wide range of adverse effects in the health—from embryotoxicity and teratogenicity to neurotoxicity—of animals an...
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Article
Melatonin decreases the oxidative stress produced by 2,4-dichlorophenoxyacetic acid in rat cerebellar granule cells
2,4-Dichlorophenoxyacetic acid (2,4-D) is one of the most widely used herbicides due to its relatively moderate toxicity and to its biodegrad-ability in the soil. In toxic concentrations, 2,4- D displays stron...
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Article
Apoptosome inactivation rescues proneural and neural cells from neurodegeneration
Deficiency of the apoptosome component Apaf1 leads to accumulation of supernumerary brain cells in mouse embryos. We observed that neural precursor cells (NPCs) in Apaf1−/− embryos escape programmed cell death, p...
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Article
5-HT1-Receptor Agonist Sumatriptan Modifies Gastric Size After 500 ml of Water in Dyspeptic Patients and Normal Subjects
Sumatriptan, a 5-HT1-receptor agonist has been shown to delay gastric emptying of liquids and solids in humans. However, no data are available of the effect of sumatriptan on gastric adaptation after distension w...
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Effectiveness of a home-based strengthening program for elderly males in Italy. A preliminary study
Background and aims: The practice of regular physical exercise has been shown to be effective in slowing the age-related progressive functional deterioration. Most exercise trials have been condu...
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Article
IAPs are essential for GDNF-mediated neuroprotective effects in injured motor neurons in vivo
During embryonic development, and in certain neurodegenerative diseases, neurons die by apoptosis1. A new family of anti-apoptotic proteins, termed inhibitors of apoptosis (IAP), suppresses apoptosis through the ...
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Article
Inhibition of phosphoinositide 3-kinase impairs pre-commitment cell cycle traverse and prevents differentiation in erythroleukaemia cells
During the early hours after exposure to differentiation inducing agents, Friend erythroleukaemia cells undergo alterations which commit them to cessation of growth and development of the characteristics of di...
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A Study of the Dual Role of Copper in Superoxide Dismutase as Antioxidant and Pro-Oxidant in Cellular Models of Amyotrophic Lateral Sclerosis
All living organisms require dietary copper for continued growth and development. This nutritional requirement arises from the essential role of the metal in the function of cuproenzymes, which play a critical...
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The Release of Nad· Radical is the Limiting Step in the Redox Reaction Between Fe(III) Cytochrome C and NADH
Water neutral solutions of Fe(III) Cytochrome c, in the presence of large excess of NADH gave the spectral changes typical of the reduction of the hemoprotein either in the absence or in the presence of oxygen.
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Allogeneic Bone Marrow Transplantation for Leukemias and Hematologic Malignancies in Bologna
Since Feb.’83 to Dec.’84 we performed 30 allogeneic bone marrow transplants (BTM) in hematologic malignancies. All the patients (pts) were HLA identical, MLR negative with the donor sibling. Conditioning follo...