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Open AccessCancer incidence and mortality in patients with insulin-treated diabetes: a UK cohort study
Raised risks of several cancers have been found in patients with type II diabetes, but there are few data on cancer risk in type I diabetes. We conducted a cohort study of 28 900 UK patients with insulin-treat...
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Article
Mortality from heart disease in a cohort of 23,000 patients with insulin-treated diabetes
Although ischaemic heart disease is the predominant cause of mortality in older people with diabetes, age-specific mortality rates have not been published for patients with Type 1 diabetes. The Diabetes UK coh...
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Article
Geographical variation in lower extremity amputation rates across four English centres among persons with and without diabetes: a population-based prevalence study
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Article
Comparative incidence of Type I diabetes in children aged under 15 years from South Asian and White or Other ethnic backgrounds in Leicestershire, UK, 1989 to 1998
Estimates of incidence of Type I (insulin-dependent) diabetes mellitus in childhood populations vary around the world. This study aimed to estimate and compare the incidence of Type I diabetes in Leicestershi...
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Article
Pancreatic islet autotransplantation combined with total pancreatectomy for the treatment of chronic pancreatitis – the Leicester experience
Islet autotransplantation offers the potential for preventing the surgically induced diabetes that is an inevitable consequence of total pancreatectomy. This paper describes the first islet autotransplant prog...
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Article
Prevalance of diabetes in elderly patients requiring permanent cardiac pacemaker insertion
Diabetes mellitus increases the rate of atrioventricular block after a myocardial infarction; right bundle branch block is more common than expected in the diabetic outpatient population. We decided to assess ...
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The effect of insulin on the vascular reactivity of isolated resistance arteries taken from healthy volunteers
Impaired reactivity of the resistance vasculature may contribute to the development of diabetic microangiopathy by altering microvascular haemodynamics. This study investigates the acute effects of insulin on ...