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  1. Article

    Open Access

    N -acetyltransferase 2 and bladder cancer: an overview and consideration of the evidence for gene–environment interaction

    Genetic polymorphism of the carcinogen metabolizing enzyme N -acetyl transferase 2 (NAT2) may influence susceptibility to bladder cancers related to smoking or to occupational exposure to arylamine carcinogens. T...

    J Green, E Banks, A Berrington, S Darby, H Deo, R Newton in British Journal of Cancer (2000)

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  2. Article

    Open Access

    Marimastat in recurrent colorectal cancer: exploratory evaluation of biological activity by measurement of carcinoembryonic antigen

    Marimastat is a specific inhibitor of matrix metalloproteinases that has been shown to be effective in cancer models. A pilot, escalating-dose study of oral marimastat was performed in patients with recurrent ...

    J N Primrose, H Bleiberg, F Daniel, S Van Belle, J L Mansi… in British Journal of Cancer (1999)

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