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Open AccessMutations in CRBN and other cereblon pathway genes are infrequently associated with acquired resistance to immunomodulatory drugs
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Introduction of a head and neck cancer dental screening pro forma
Discusses a dental screening pro forma.
Highlights the current guidelines for head and neck cancer patients...
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Article
Treatment of multiple myeloma with adoptively transferred chimeric NKG2D receptor-expressing T cells
Multiple myeloma causes approximately 10% of all hematologic malignancies. We have previously shown that human T cells expressing chimeric NKG2D receptors (chNKG2D) consisting of NKG2D fused to the CD3ζ cytopl...
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Lipoic acid prevents body weight gain induced by a high fat diet in rats: Effects on intestinal sugar transport
Several studies have suggested that oxidative stress might cause and aggravate the inflammatory state associated with obesity and could be the link between excessive weight gain and its related disorders such ...
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Leptin effect on intestinal galactose absorption in ob/ob and db/db mice
Our previous works demonstrated that leptin inhibits galactose absorption in rat and mice intestinal rings. Here, we have studied the effect of exogenous leptin on intestinal galactose absorption in the geneti...
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Article
Transport of Proline and Hydroxyproline by the Neutral Amino-acid Exchanger ASCT1
ASCT1 is a member of the glutamate transporter superfamily cloned from human brain and characterized as a Na+-dependent neutral amino-acid exchanger, which displays substrate-induced chloride-channel activity and...
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Functional expression of the short isoform of the murine leptin receptor Ob-Rc (muB1.219) inXenopus laevis oocytes
Leptin, a hormone mainly secreted by the adipose tissue, acts on the hypothalamus to regulate food intake and thermogenesis. Six leptin receptor isoforms have been identified and localized in different tissues...
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Cytokine effect on intestinal galactose absorption
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Leptin effect on galactose absorption in mice jejunum
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Cytoskeleton involvement on intestinal absorption processes
It has been recently demonstrated in the laboratory that the cytoskeletal inhibitor cytochalasin E has an indirect inhibitory effect on the function of the intestinal Na+-sugar cotransporter (SGLT1). The present ...
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Growth factors and receptors in ovarian cancer
Repair of the normal ovarian epithelium, subsequent to the damage inflicted by ovulation, is thought to be carried out by epidermal growth factor (EGF) acting through its receptor (EGFR). In many tumour cells,...
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Article
Monoamine containing varicosities in the neural sheath of a gastropod mollusc demonstrated by glyoxylic acid histofluorescence
The glyoxylic acid monoamine-detecting technique of Bolstad et al. (1979) was applied to wholemounts of intact ganglia of the gastropod mollusc Philine aperta. A dense network of fluorescent varicosities was foun...
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Article
Nitrogen Metabolism in Preterm Infants Fed Human Donor Breast Milk: the Possible Essentiality of Glycine
Summary: Nitrogen metabolism was studied in three preterm infants (mean gestation 32 wk) by the method of consecutive metabolic balance. The absorption and retention of nitrogen from breast milk was measured, ...
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Article
MICROMETHOD FOR DETERMINATION OF PLASMA ZINC IN PRETERM INFANTS
Atomic absorption spectrophotometry (A.A.S.) flame techniques use 0·2-0·5 ml plasma. A.A.S. with Electrothermal atomisation is more sensitive and requires <20 μ1 of plasma, but contamination is a problem and i...
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Production of Positron and Electron Pairs by Bombardment of Mercury with β-Particles of Low Energy
SKOBELZYN and Stepanowa1 have reported the production of positrons when β-particles of energy 1–3 MV. im**e on solid lead. In order to conserve electric charge, the phenomenon rmist have involved the production...