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  1. Article

    Open Access

    Reactive oxygen species delay control of lymphocytic choriomeningitis virus

    Cluster of differentiation (CD)8+ T cells are like a double edged sword during chronic viral infections because they not only promote virus elimination but also induce virus-mediated immunopathology. Elevated lev...

    P A Lang, H C Xu, M Grusdat, D R McIlwain, A A Pandyra… in Cell Death & Differentiation (2013)

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  2. Article

    Open Access

    IRF4 and BATF are critical for CD8+ T-cell function following infection with LCMV

    CD8+ T-cell functions are critical for preventing chronic viral infections by eliminating infected cells. For healthy immune responses, beneficial destruction of infected cells must be balanced against immunopath...

    M Grusdat, D R McIlwain, H C Xu, V I Pozdeev, J Knievel… in Cell Death & Differentiation (2014)

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  3. Article

    Toso regulates differentiation and activation of inflammatory dendritic cells during persistence-prone virus infection

    During virus infection and autoimmune disease, inflammatory dendritic cells (iDCs) differentiate from blood monocytes and infiltrate infected tissue. Following acute infection with hepatotropic viruses, iDCs a...

    P A Lang, A Meryk, A A Pandyra, D Brenner, A Brüstle… in Cell Death & Differentiation (2015)

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