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Open AccessRelationship between hemolysis and lipid oxidation in red blood cell-spiked fish muscle; dependance on pH and blood plasma
The relationship between hemolysis and lipid oxidation was explored in red blood cell (RBCs)-spiked washed cod mince (WCM). At pH 6.8 and 3 ± 1 °C, intact RBCs (71 µM Hb) delayed lipid oxidation by 1 day compa...
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Article
Open AccessA chromosome-level genome assembly of a free-living white-crowned sparrow (Zonotrichia leucophrys gambelii)
The white-crowned sparrow, Zonotrichia leucophrys, is a passerine bird with a wide distribution and it is extensively adapted to environmental changes. It has historically acted as a model species in studies on a...
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Article
Open AccessStructural variants involved in high-altitude adaptation detected using single-molecule long-read sequencing
Structural variants (SVs), accounting for a larger fraction of the genome than SNPs/InDels, are an important pool of genetic variation, enabling environmental adaptations. Here, we perform long-read sequencing...
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Open AccessResearch on the control strategy of DC microgrids with distributed energy storage
As a supplement to large power grids, DC microgrids with new energy access are increasingly widely used. However, with the increasing proportion of new energy in DC microgrids, its output fluctuations directly...
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Article
Open AccessH3.1K27me1 loss confers Arabidopsis resistance to Geminivirus by sequestering DNA repair proteins onto host genome
The H3 methyltransferases ATXR5 and ATXR6 deposit H3.1K27me1 to heterochromatin to prevent genomic instability and transposon re-activation. Here, we report that atxr5 atxr6 mutants display robust resistance to G...
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Article
Enantioselective [2+2]-cycloadditions with triplet photoenzymes
Naturally evolved enzymes, despite their astonishingly large variety and functional diversity, operate predominantly through thermochemical activation. Integrating prominent photocatalysis modes into proteins,...
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Article
Open AccessExportin 4 depletion leads to nuclear accumulation of a subset of circular RNAs
Numerous RNAs are exported from the nucleus, abnormalities of which lead to cellular complications and diseases. How thousands of circular RNAs (circRNAs) are exported from the nucleus remains elusive. Here, w...
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Article
Open AccessExploring how plasma- and muscle-related parameters affect trout hemolysis as a route to prevent hemoglobin-mediated lipid oxidation of fish muscle
Hemoglobin (Hb) is a powerful promoter of lipid oxidation, particularly in muscle of small pelagic fish species and fish by-products, both having high Hb-levels and highly unsaturated lipids. As Hb is located ...
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Article
Open AccessNitrogen-rich energetic polymer powered aluminum particles with enhanced reactivity and energy content
Aluminum particles are of significant interest in enhancing the energy release performance of explosives. One of the major impediments to their use is that Al2O3 shell significantly decreases overall performance....
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Article
Activation of TIR signalling boosts pattern-triggered immunity
Plant immune responses are mainly activated by two types of receptor. Pattern recognition receptors localized on the plasma membrane perceive extracellular microbial features, and nucleotide-binding leucine-ri...
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Article
Open AccessHemoglobin-mediated lipid oxidation of herring filleting co-products during ensilaging and its inhibition by pre-incubation in antioxidant solutions
The aims of this study were to investigate the role of hemoglobin (Hb) in lipid oxidation development during ensilaging of herring filleting co-products, and, to inhibit this reaction by pre-incubating the co-...
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Article
Open AccessOutcome of endovascular treatment within and beyond 6 h without perfusion software
Endovascular treatment (EVT) has been accepted as the standard of care for patients with acute ischemic stroke. The aim of the present study was to compare clinical outcomes of patients who received EVT within...
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Article
Open AccessFast sulfate formation from oxidation of SO2 by NO2 and HONO observed in Bei**g haze
Severe events of wintertime particulate air pollution in Bei**g (winter haze) are associated with high relative humidity (RH) and fast production of particulate sulfate from the oxidation of sulfur dioxide (SO2)...
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Open AccessUltrasmall copper-based nanoparticles for reactive oxygen species scavenging and alleviation of inflammation related diseases
Oxidative stress is associated with many acute and chronic inflammatory diseases, yet limited treatment is currently available clinically. The development of enzyme-mimicking nanomaterials (nanozymes) with goo...
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Open AccessBlood-triggered generation of platinum nanoparticle functions as an anti-cancer agent
Since the discovery of metal nanoparticles (NPs) in the 1960s, unknown toxicity, cost and the ethical hurdles of research in humans have hindered the translation of these NPs to clinical use. In this work, we ...
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Article
Open AccessIdentification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma
Previous studies from the Cancer Cell Line Encyclopedia (CCLE) project have adopted commercial pan-cancer cell line models to identify drug sensitivity biomarkers. However, drug sensitivity biomarkers in esoph...
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Article
Open AccessElevated preoperative platelet distribution width predicts poor prognosis in Esophageal Squamous Cell Carcinoma
Activated platelets play a multifaceted role in tumorigenesis and progression. Platelet distribution width (PDW) is generally applied platelet parameters from routine blood test. Preoperative PDW has been cons...
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Article
Open AccessEfficacy of Recombinant Human BMP2 and PDGF-BB in Orofacial Bone Regeneration: A Systematic Review and Meta-analysis
With the rapid development of tissue engineering therapies, there is a growing interest in the application of recombinant human growth factors (rhGFs) to regenerate human orofacial bones. However, despite repo...
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Open AccessAuthor Correction: Infection of microglia with Porphyromonas gingivalis promotes cell migration and an inflammatory response through the gingipain-mediated activation of protease-activated receptor-2 in mice
A correction to this article has been published and is linked from the HTML and PDF version of this paper. The error has been fixed in the paper.
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Open AccessInvestigation of the prevalence of Cognitive Impairment and its risk factors within the elderly population in Shanghai, China
To investigate the prevalence of cognitive impairment and its risk factors among Chinese elders aged over 80 years, a community-based, cross-sectional study was conducted from May to June 2016 in Shanghai, Chi...