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Article
Open AccessSelf-assembled dendrimer polyamide nanofilms with enhanced effective pore area for ion separation
Membrane technology using well-defined pore structure can achieve high ion purity and recovery. However, fine-tuning the inner pore structure of the separation nanofilm to be uniform and enhance the effective ...
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Article
Open AccessExploration of key factors in Gingival Crevicular fluids from patients undergoing Periodontally Accelerated Osteogenic Orthodontics (PAOO) using proteome analysis
The aims of this study are to explore protein changes in gingival crevicular fluid at different time points after PAOO by proteomics method and to select significant bone metabolization-related biomarkers.
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Article
Open AccessIGF1R-phosphorylated PYCR1 facilitates ELK4 transcriptional activity and sustains tumor growth under hypoxia
The proline synthesis is importantly involved in tumor growth under hypoxia, while the underlying mechanism remains to be further investigated. Here we show that pyrroline-5-carpoxylate reductase-1 (PYCR1), di...
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Article
Open AccessFeasibility and safety of uniportal thoracoscopy for chronic pulmonary aspergillosis
Surgery plays a crucial role in the treatment of patients with chronic pulmonary aspergillosis (CPA). However, there is currently limited information available regarding the use of uniportal thoracoscopy (Uni-...
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Article
Open AccessThe effect of low-frequency high-intensity ultrasound combined with aspirin on tooth movement in rats
Given the difficulties or incapacity of teeth movement in orthodontic treatment, the ways to speed tooth movement must be investigated. Besides, nonsteroidal anti-inflammatory drugs (NSAIDs) were utilized to t...
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Open AccessOpen decortication for patients presenting with stage III tuberculous empyema with low density lines on CT imaging
To explore the influence of CT findings on the optimal timing of open decorticationin patients with stage III tuberculous empyema. A total of 80 patients with stage III tuberculous empyema who had undergone op...
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Open AccessIs VATS suitable for lung diseases with hemoptysis? Experience from a hemoptysis treatment center in China
Surgery is crucial in the treatment of the potentially fatal pulmonary hemoptysis condition. Currently, most patients with hemoptysis are treated by traditional open surgery (OS). To illustrate the effectivene...
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Article
Open AccessNanoparticle-mediated TRPV1 channel blockade amplifies cancer thermo-immunotherapy via heat shock factor 1 modulation
The survival of malignant tumors is highly dependent on their intrinsic self-defense pathways such as heat shock protein (HSP) during cancer therapy. However, precisely dismantling self-defenses to amplify ant...
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Open AccessAge-specific effects on adverse pregnancy outcomes vary by maternal characteristics: a population-based retrospective study in **amen, China
Advanced maternal age (AMA; ≥35 years) is considered to be a major risk factor for adverse pregnancy outcomes. Along with the global trend of delayed childbearing, and in particular, the implementation of Chin...
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Article
Open AccessHypoglycemia unawareness identified by continuous glucose monitoring system is frequent in outpatients with type 2 diabetes without receiving intensive therapeutic interventions
Patients with diabetes are prone to asymptomatic hypoglycemia (AH) due to diminished ability to perceive the onset of hypoglycemia. However, the actual prevalence and influencing factors of AH in outpatients w...
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Article
NEAWalk: Inferring missing social interactions via topological-temporal embeddings of social groups
Real-world network data consisting of social interactions can be incomplete due to deliberately erased or unsuccessful data collection, which cause the misleading of social interaction analysis for many variou...
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Open AccessGFAT1-linked TAB1 glutamylation sustains p38 MAPK activation and promotes lung cancer cell survival under glucose starvation
Reprogrammed cell metabolism is deemed as one of the hallmarks of cancer. Hexosamine biosynthesis pathway (HBP) acts as an “energy sensor” in cells to regulate metabolic fluxes. Glutamine-fructose-6-phosphate ...
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Article
Open AccessProbability model of rock climbing recognition based on information fusion sensor time series
Rock climbing is a sports activity that integrates competition, entertainment, and culture. With the development of the economy and the improvement in living standards, rock climbing has embarked on a path of ...
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Article
Open AccessCorrection to: c-Src confers resistance to mitotic stress through inhibition of DMAP1/Bub3 complex formation in pancreatic cancer
Following publication of the work [1], authors reported the “flow cytometery plots” panel in Fig. 4e contained an inter-duplication in error.
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Open AccessC-Src confers resistance to mitotic stress through inhibition DMAP1/Bub3 complex formation in pancreatic cancer
Chromatin modification at mitosis is closely related to transcriptional reactivation in the subsequent cell cycle. We reasoned this process is deregulated by oncogenic signals, which would contribute to mitoti...
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Author Correction: Local generation of fumarate promotes DNA repair through inhibition of histone H3 demethylation
In the version of this Article originally published, the authors mistakenly used the same images for three different time points in Fig. 2d: images for 24 h post-IR WT were also used for 0 h post-IR WT (top ro...
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Article
Open AccessPKCε phosphorylates MIIP and promotes colorectal cancer metastasis through inhibition of RelA deacetylation
EGFR signaling is implicated in NF-κB activation. However, the concrete mechanisms by which the core transducer of NF-κB signaling pathway, RelA/p65 is regulated under EGFR activation remains to be further cla...
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Correction: Corrigendum: A splicing switch from ketohexokinase-C to ketohexokinase-A drives hepatocellular carcinoma formation
Nature Cell Biology 18, 561–571 (2016); published online 18 April 2016; corrected after print 27 April 2016 In the version of this Article originally published, the affiliations for Gilbert Cote, Hongxia Wang ...
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Article
PAQR10 and PAQR11 mediate Ras signaling in the Golgi apparatus
Ras plays a pivotal role in many cellular activities, and its subcellular compartmentalization provides spatial and temporal selectivity. Here we report a mode of spatial regulation of Ras signaling in the Gol...
