7 Result(s)
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Article
Open AccessSelf-assembled dendrimer polyamide nanofilms with enhanced effective pore area for ion separation
Membrane technology using well-defined pore structure can achieve high ion purity and recovery. However, fine-tuning the inner pore structure of the separation nanofilm to be uniform and enhance the effective ...
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Article
Open AccessIGF1R-phosphorylated PYCR1 facilitates ELK4 transcriptional activity and sustains tumor growth under hypoxia
The proline synthesis is importantly involved in tumor growth under hypoxia, while the underlying mechanism remains to be further investigated. Here we show that pyrroline-5-carpoxylate reductase-1 (PYCR1), di...
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Article
Open AccessFeasibility and safety of uniportal thoracoscopy for chronic pulmonary aspergillosis
Surgery plays a crucial role in the treatment of patients with chronic pulmonary aspergillosis (CPA). However, there is currently limited information available regarding the use of uniportal thoracoscopy (Uni-...
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Article
Open AccessOpen decortication for patients presenting with stage III tuberculous empyema with low density lines on CT imaging
To explore the influence of CT findings on the optimal timing of open decorticationin patients with stage III tuberculous empyema. A total of 80 patients with stage III tuberculous empyema who had undergone op...
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Article
Open AccessNanoparticle-mediated TRPV1 channel blockade amplifies cancer thermo-immunotherapy via heat shock factor 1 modulation
The survival of malignant tumors is highly dependent on their intrinsic self-defense pathways such as heat shock protein (HSP) during cancer therapy. However, precisely dismantling self-defenses to amplify ant...
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Article
Open AccessPKCε phosphorylates MIIP and promotes colorectal cancer metastasis through inhibition of RelA deacetylation
EGFR signaling is implicated in NF-κB activation. However, the concrete mechanisms by which the core transducer of NF-κB signaling pathway, RelA/p65 is regulated under EGFR activation remains to be further cla...
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Article
PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells
Pyruvate kinase M2 (PKM2) is expressed at high levels during embryonic development and tumour progression and is important for cell growth. However, it is not known whether it directly controls cell division. ...
