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Article
RNAi screens identify HES4 as a regulator of redox balance supporting pyrimidine synthesis and tumor growth
NADH/NAD+ redox balance is pivotal for cellular metabolism. Systematic identification of NAD(H) redox regulators, although currently lacking, would help uncover unknown effectors critically implicated in the coor...
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Article
Effect of prior lenalidomide or daratumumab exposure on hematopoietic stem cell collection and reconstitution in multiple myeloma
The roles of Lenalidomide (Len) and Daratumumab (Dara) in multiple myeloma treatment are well-established, yet their influences on hematopoietic stem cell harvesting and reconstitution remain disputed.
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Article
Open AccessSelf-assembled dendrimer polyamide nanofilms with enhanced effective pore area for ion separation
Membrane technology using well-defined pore structure can achieve high ion purity and recovery. However, fine-tuning the inner pore structure of the separation nanofilm to be uniform and enhance the effective ...
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Chapter and Conference Paper
Early Warning Strategy for Thermal Runaway of Lithium-Ion Battery Packs
Lithium-ion batteries have a series of advantages such as high specific energy, light weight, environmental protection and safety, no memory effect, and stable performance. The thermal runaway of lithium-ion b...
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Chapter and Conference Paper
Ultrasensitive Terahertz Detection via Different Novel Metasurfaces
In recent decades, Terahertz (THz) bioanalytical sensors are considered as an excellent sensing platform due to the advantages such as label-free, accurate, nonionizing, high signal to noise ratio, and non-dam...
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Article
Open AccessExploration of key factors in Gingival Crevicular fluids from patients undergoing Periodontally Accelerated Osteogenic Orthodontics (PAOO) using proteome analysis
The aims of this study are to explore protein changes in gingival crevicular fluid at different time points after PAOO by proteomics method and to select significant bone metabolization-related biomarkers.
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Article
An eco-friendly cellulose-based hybrid membrane derived from waste bagasse for wearable applications
Sugarcane, as one of the most important crops in the world, plays an important role in the economy around the world. However, huge waste and low treatment efficiency put forward new requirements for bagasse tr...
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Article
Open AccessIGF1R-phosphorylated PYCR1 facilitates ELK4 transcriptional activity and sustains tumor growth under hypoxia
The proline synthesis is importantly involved in tumor growth under hypoxia, while the underlying mechanism remains to be further investigated. Here we show that pyrroline-5-carpoxylate reductase-1 (PYCR1), di...
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Article
Open AccessFeasibility and safety of uniportal thoracoscopy for chronic pulmonary aspergillosis
Surgery plays a crucial role in the treatment of patients with chronic pulmonary aspergillosis (CPA). However, there is currently limited information available regarding the use of uniportal thoracoscopy (Uni-...
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Article
Open AccessThe effect of low-frequency high-intensity ultrasound combined with aspirin on tooth movement in rats
Given the difficulties or incapacity of teeth movement in orthodontic treatment, the ways to speed tooth movement must be investigated. Besides, nonsteroidal anti-inflammatory drugs (NSAIDs) were utilized to t...
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Article
Open AccessOpen decortication for patients presenting with stage III tuberculous empyema with low density lines on CT imaging
To explore the influence of CT findings on the optimal timing of open decorticationin patients with stage III tuberculous empyema. A total of 80 patients with stage III tuberculous empyema who had undergone op...
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Article
Open AccessIs VATS suitable for lung diseases with hemoptysis? Experience from a hemoptysis treatment center in China
Surgery is crucial in the treatment of the potentially fatal pulmonary hemoptysis condition. Currently, most patients with hemoptysis are treated by traditional open surgery (OS). To illustrate the effectivene...
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Article
The negative effect of G1958A polymorphism on MTHFD1 protein stability and HCC growth
Methylenetetrahydrofolate dehydrogenase (MTHFD1), a key enzyme on the folate pathway, has been implicated in the tumor development of distinct types of cancers. The single nucleotide polymorphism (SNP) of 1958...
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Article
Open AccessNanoparticle-mediated TRPV1 channel blockade amplifies cancer thermo-immunotherapy via heat shock factor 1 modulation
The survival of malignant tumors is highly dependent on their intrinsic self-defense pathways such as heat shock protein (HSP) during cancer therapy. However, precisely dismantling self-defenses to amplify ant...
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Article
Open AccessAge-specific effects on adverse pregnancy outcomes vary by maternal characteristics: a population-based retrospective study in **amen, China
Advanced maternal age (AMA; ≥35 years) is considered to be a major risk factor for adverse pregnancy outcomes. Along with the global trend of delayed childbearing, and in particular, the implementation of Chin...
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Article
Accuracy of integration of dental cast and cephalograms compared with cone-beam computed tomography: a comparative study
This study proposes a method that integrates maxillary dental cast and cephalograms and evaluates its accuracy compared with cone-beam computed tomography (CBCT) scans. The study sample comprised 20 adult pati...
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Chapter and Conference Paper
Meta-Path Based Social Relation Reasoning in a Deep and Robust Way
Social relation reasoning in heterogeneous social networks (HSNs) should not only infer whether people are connected, but also why they know each other and what their relationship is. This task is challenging ...
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Article
Open AccessHypoglycemia unawareness identified by continuous glucose monitoring system is frequent in outpatients with type 2 diabetes without receiving intensive therapeutic interventions
Patients with diabetes are prone to asymptomatic hypoglycemia (AH) due to diminished ability to perceive the onset of hypoglycemia. However, the actual prevalence and influencing factors of AH in outpatients w...
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Article
NEAWalk: Inferring missing social interactions via topological-temporal embeddings of social groups
Real-world network data consisting of social interactions can be incomplete due to deliberately erased or unsuccessful data collection, which cause the misleading of social interaction analysis for many variou...
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Article
Open AccessGFAT1-linked TAB1 glutamylation sustains p38 MAPK activation and promotes lung cancer cell survival under glucose starvation
Reprogrammed cell metabolism is deemed as one of the hallmarks of cancer. Hexosamine biosynthesis pathway (HBP) acts as an “energy sensor” in cells to regulate metabolic fluxes. Glutamine-fructose-6-phosphate ...
