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Article
Viral metagenomics reveals significant viruses in the genital tract of apparently healthy dairy cows
The virome in genital tract secretion samples collected from 80 dairy cattle in Shanghai, China, was characterized. Viruses detected included members of the families Papillomaviridae, Polyomaviridae, Hepeviridae,...
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Article
Open AccessEntry of sapelovirus into IPEC-J2 cells is dependent on caveolae-mediated endocytosis
Porcine sapelovirus (PSV), a species of the genus Sapelovirus within the family Picornaviridae, are a significant cause of enteritis, pneumonia, polioencephalomyelitis and reproductive disorders in pigs. Howev...
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Article
Open AccessMolecular characterization of a porcine teschovirus HuN-1 isolate proliferating in PK-15 cell
Porcine teschoviruses (PTVs) are small non-enveloped viruses with single-stranded, positive sense genomic RNA, belonging to the family Picornaviridae. Natural infections of teschoviruses are limited to pigs.
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Article
Open AccessPlasma virome of cattle from forest region revealed diverse small circular ssDNA viral genomes
Free-range cattle are common in the Northeast China area, which have close contact with farmers and may carry virus threatening to cattle and farmers.
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Article
Open AccessVirome comparisons in wild-diseased and healthy captive giant pandas
The giant panda (Ailuropoda melanoleuca) is a vulnerable mammal herbivore living wild in central China. Viral infections have become a potential threat to the health of these endangered animals, but limited infor...
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Article
Viral metagenomics analysis of feces from coronary heart disease patients reveals the genetic diversity of the Microviridae
Recent studies have declared that members of the ssDNA virus family Microviridae play an important role in multiple environments, as they have been found taking a dominant position in the human gut. The aim of th...
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Article
Open AccessGenomic organization and recombination analysis of a porcine sapovirus identified from a piglet with diarrhea in China
Sapovirus (SaV), a member of the family Caliciviridae, is an etiologic agent of gastroenteritis in humans and pigs. To date, both intra- and inter-genogroup recombinant strains have been reported in many countrie...
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Article
Open AccessIdentification and genomic characterization of a novel species of feline anellovirus
Here, a novel feline anellovirus strain (named FelineAV621 and GenBank no. KX262893) was detected in two cats with diarrhea. The complete genome of FelineAV621 is 2409 nt long with a G+C content of 56.67 %, in...
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Article
New serotypes of porcine teschovirus identified in Shanghai, China
Teschoviruses are widely endemic and commonly found in pig fecal samples. In this study, we collected fecal specimens from various pig herds and genotyped them based on the VP1 gene. Of 322 samples, 276 were posi...
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Article
Open AccessDiagnostic application of PIK3CA mutation analysis in Chinese esophageal cancer patients
The PIK3CA gene mutation was found to associate with prognosis and might affect molecular targeted therapy in esophageal carcinoma (EC). The aim of this study is to compare different methods for analyzing the PIK...
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Article
Molecular detection of genogroup I and II picobirnaviruses in pigs in China
In this study, a total of 187 stool specimens were collected from a pig farm in Hunan province of China, from November 2011 to June 2012. 39 (20.9 %) stool specimens were positive for picobirnaviruses using re...
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Article
Reston virus in domestic pigs in China
Historically, Reston virus (RESTV) has been found to be associated with outbreaks of disease only in nonhuman primates. Its spread to domestic pigs was reported for the first time in 2008. In this study, we re...
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Article
Molecular characterization and phylogenetic analysis of the genome of porcine torovirus
In this study, we amplified and sequenced the first genome of porcine torovirus (PToV SH1 strain). The genome was found to be 28,301 bp in length, sharing 79 % identity with Breda virus. It mainly consists of...
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Article
Microarray analysis of differentially expressed transcripts in porcine intestinal epithelial cells (IPEC-J2) infected with porcine sapelovirus as a model to study innate immune responses to enteric viruses
The local intestinal mucosa, the largest mucosal immune system in animals, plays an important role in resistance against intestinal pathogen infection. However, the molecular antiviral mechanisms of the intest...
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Article
Open AccessPrevalence of porcine enterovirus 9 in pigs in Middle and Eastern China
Little information on the epidemiology and pathogenicity of porcine enterovirus 9 (PEV-9) is available. The present study investigated the prevalence of PEV-9 in pig populations in middle and eastern China usi...
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Article
Lipopolysaccharide-induced inflammation of bronchi and emphysematous changes of pulmonary parenchyma in miniature pigs (Sus scrofa domestica)
Lipopolysaccharide (LPS) is widely used to induce chronic obstructive pulmonary disease (COPD) in animal models. Rodents are most commonly used to model COPD, but their substantial anatomic and physiological d...
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Article
Open AccessRecombinant porcine norovirus identified from piglet with diarrhea
Noroviruses (NoVs) are members of the family Caliciviridae and are emerging enteric pathogens of humans and animals. Some porcine NoVs are genetically similar to human strains and are classified into GII, like mo...
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Article
Frequency and characterization of porcine hokovirus (PHoV) in domestic pigs in eastern China
This study reports the frequency and age distribution of porcine hokovirus (PHoV) in domestic pigs and characterizes the strains prevalent in eastern China. A total of 242 tissues from domestic pigs were teste...
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Article
Molecular detection of Torque teno mini virus (TTMV) in China
In this study, 176 serum specimens were collected from hospitalized cardiovascular diseases patients in Shanghai, China. 140 samples (79.5%) were positive with the primers located in non-coding region, and 30 ...
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Article
Molecular characterization of a porcine kobuvirus strain in China
Porcine kobuvirus was first identified in 2007 in Hungary. The virus has been detected in several Asian countries. In our study, the complete genome of the recently identified porcine kobuvirus strain SH-W-CHN...
