668 Result(s)
within
**sheng Zhang
Life Sciences
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Article
A KLF2-BMPER-Smad1/5 checkpoint regulates high fluid shear stress-mediated artery remodeling
Vascular remodeling to match arterial diameter to tissue requirements commonly fails in ischemic disease. Endothelial cells sense fluid shear stress (FSS) from blood flow to maintain FSS within a narrow range ...
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Open AccessEffects of altering the ratio of C16:0 and cis-9 C18:1 in rumen bypass fat on growth performance, lipid metabolism, intestinal barrier, cecal microbiota, and inflammation in fattening bulls
C16:0 and cis-9 C18:1 may have different effects on animal growth and health due to unique metabolism in vivo. This study was investigated to explore the different effects of altering the ratio of C16:0 and cis-9...
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Open AccessGenome-wide identification and expression analysis of histone deacetylase and histone acetyltransferase genes in response to drought in poplars
Histone deacetylases (HDACs) and histone acetyltransferases (HATs) are involved in plant growth and development as well as in response to environmental changes, by dynamically regulating gene acetylation level...
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Open AccessTranscriptome and differential expression analysis revealed the pathogenic-related genes in Magnaporthe oryzae during leaf and panicle infection
Magnaporthe oryzae is one of the most destructive pathogens that threaten rice production around the world. Previous studies mainly focus on pathogenic mechanism of M. oryzae during infection on rice at leaf stag...
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Application of Repetitive Sequences in Fish Cell Depletion as a Target for the CRISPR/Cas9 System
Specific cell depletion is a common means to study the physiological function of cell lineages and tissue regeneration. However, 100% depletion is difficult to achieve with existing cell depletion strategies. ...
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Article
Hormonal regulation changes in shrimp infected with Enterocytozoon hepatopenaei: a transcriptomic analysis
Enterocytozoon hepatopenaei (EHP) is a fungal pathogen that causes hepatopancreatic microsporidiosis (HPM) in shrimp, resulting in significant economic losses for the shrimp culture industry. Although the impact...
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Article
Major quantitative trait locus qLA3.1 is related to tomato leaf angle by regulating cell length at the petiole base
qLA3.1, controlling leaf angle in tomato, was fine-mapped to an interval of 4.45 kb on chromosome A03, and one gene encoding auxin response factor was identified as a candidate gene.
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Open AccessA MYB-related transcription factor ZmMYBR29 is involved in grain filling
The endosperm serves as the primary source of nutrients for maize (Zea mays L.) kernel embryo development and germination. Positioned at the base of the endosperm, the transfer cells (TCs) of the basal endosperm ...
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Article
Open AccessYOD1 protects against MRSA sepsis-induced DIC through Lys33-linked deubiquitination of NLRP3
Disseminated intravascular coagulation (DIC) is considered to be the most common and lethal complication of sepsis. NLR-family pyrin domain-containing-3 (NLRP3) inflammasome plays an important role in host def...
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Article
A Multi-view Molecular Pre-training with Generative Contrastive Learning
Molecular representation learning can preserve meaningful molecular structures as embedding vectors, which is a necessary prerequisite for molecular property prediction. Yet, learning how to accurately represe...
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Article
lncRNA MIAT promotes luminal B breast cancer cell proliferation, migration, and invasion in vitro
Long noncoding RNAs (lncRNAs) play a role in the emergence and progression of several human tumors, including luminal B breast cancer (BC). The biological functions and potential mechanisms of lncRNA myocardia...
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Article
Impacts of Spectral Characteristics of Dissolved Organic Matter on Methyl Mercury Contents in Permafrost Wetlands, Northeast China
Dissolved organic matter (DOM) plays an important role in promoting or suppressing methylmercury (MeHg) production in wetlands. However, in the context of climate warming, the regulatory mechanism of DOM compo...
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Open AccessCis-eQTLs in seven duck tissues identify novel candidate genes for growth and carcass traits
Expression quantitative trait loci (eQTL) studies aim to understand the influence of genetic variants on gene expression. The colocalization of eQTL map** and GWAS strategy could help identify essential cand...
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Article
Pilot study assessing effects of selected soil factors on the accumulation of hesperidin, nobiletin and tangeretin in pericarps of Citrus reticulata ‘Chachi’
The aim of the study is to know about which soil factors could influence the accumulation of hesperidin, nobiletin and tangeretin in pericarps of Citrus reticulata ‘Chachi’ (Citrus reticulata cv. Chachiensis).
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Article
Open AccessKey mRNAs and lncRNAs of pituitary that affect the reproduction of FecB + + small tail han sheep
The pituitary directly regulates the reproductive process through follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Transcriptomic research on the pituitaries of ewes with different FecB (fecundity...
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Open AccessAllantoate Amidohydrolase OsAAH is Essential for Preharvest Sprouting Resistance in Rice
Preharvest sprouting (PHS) is an undesirable trait that decreases yield and quality in rice production. Understanding the genes and regulatory mechanisms underlying PHS is of great significance for breeding PH...
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Article
Prevalence and molecular characterization of Cryptosporidium spp., Enterocytozoon bieneusi, and Giardia duodenalis in dairy cattle in Ningxia, northwestern China
Cryptosporidium spp., Enterocytozoon bieneusi, and Giardia duodenalis are common intestinal pathogens that infect humans and animals. To date, research regarding these three protozoa in the Ningxia Hui Autonomous...
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Open AccessGenome-wide analysis of the NAC gene family and functional verification of the DcNAC043s in Dendrobium catenatum
The NAC (NAM, ATAF1/2 and CUC2) domain protein plays an important role in plant growth and development. The function of members of NAC gene family has been deeply studied in many plants. However, the evolutionary...
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Article
KDM4B down-regulation facilitated breast cancer cell stemness via PHGDH upregulation in H3K36me3-dependent manner
Despite recent advances have been made in clinical treatments of breast cancer, the general prognosis of patients remains poor. Therefore, it is imperative to develop a more effective therapeutic strategy. Lys...
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The Involvement of DNA Methylation in Plant Growth Regulators-Mediated Growth in Tomato (Solanum lycopersicum) Seedlings
DNA methylation is a kind of epigenetic modification regulated by DNA methyltransferases and DNA demethylases. Here, the influences of DNA methylation inhibitor 5-aza-2'-deoxycytidine (5-azadC) combined with p...
