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Open AccessNon-volatile rippled-assisted optoelectronic array for all-day motion detection and recognition
In-sensor processing has the potential to reduce the energy consumption and hardware complexity of motion detection and recognition. However, the state-of-the-art all-in-one array integration technologies with...
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Article
Open AccessNeuromorphic electro-stimulation based on atomically thin semiconductor for damage-free inflammation inhibition
Inflammation, caused by accumulation of inflammatory cytokines from immunocytes, is prevalent in a variety of diseases. Electro-stimulation emerges as a promising candidate for inflammatory inhibition. Althoug...
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Open AccessDecadal oscillation provides skillful multiyear predictions of Antarctic sea ice
Over the satellite era, Antarctic sea ice exhibited an overall long-term increasing trend, contrary to the Arctic reduction under global warming. However, the drastic decline of Antarctic sea ice in 2014–2018 ...
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Open AccessMedial open-wedge high tibial osteotomy for the treatment of degenerative varus knee osteoarthritis in geriatric patients: a retrospective study
HTO has proven to be a cost-effective surgical procedure in the treatment of KOA, but few investigations have studied radiological changes and clinical effectiveness of OWHTO in geriatric patients. 76 patients...
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Open AccessProgrammable supramolecular chirality in non-equilibrium systems affording a multistate chiroptical switch
The dynamic regulation of supramolecular chirality in non-equilibrium systems can provide valuable insights into molecular self-assembly in living systems. Herein, we demonstrate the use of chemical fuels for ...
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Open AccessOrdered creation and motion of skyrmions with surface acoustic wave
Magnetic skyrmions with a well-defined spin texture have shown unprecedented potential for various spintronic applications owning to their topologically non-trivial and quasiparticle properties. To put skyrmio...
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Open AccessA multi-strategy improved tree–seed algorithm for numerical optimization and engineering optimization problems
Tree–seed algorithm is a stochastic search algorithm with superior performance suitable for solving continuous optimization problems. However, it is also prone to fall into local optimum and slow in convergenc...
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Open AccessRabphilin-3A undergoes phase separation to regulate GluN2A mobility and surface clustering
N-methyl-D-aspartate receptors (NMDARs) are essential for excitatory neurotransmission and synaptic plasticity. GluN2A and GluN2B, two predominant Glu2N subunits of NMDARs in the hippocampus and the cortex, di...
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Open AccessCompact artificial neuron based on anti-ferroelectric transistor
Neuromorphic machines are intriguing for building energy-efficient intelligent systems, where spiking neurons are pivotal components. Recently, memristive neurons with promising bio-plausibility have been deve...
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Open AccessInfluence of root distribution patterns on soil dynamic characteristics
Slopes along the highway and railway routes are subjected to not only static loads but also dynamic loads generated by vehicles and trains. The induced excessive deformation potentially poses a threat to slope...
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Open AccessPublisher Correction: Structural basis for mismatch surveillance by CRISPR–Cas9
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Open AccessStructural basis for mismatch surveillance by CRISPR–Cas9
CRISPR–Cas9 as a programmable genome editing tool is hindered by off-target DNA cleavage1–4, and the underlying mechanisms by which Cas9 recognizes mismatches are poorly understood5–7. Although Cas9 variants with...
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Open AccessAn application-specific image processing array based on WSe2 transistors with electrically switchable logic functions
With the rapid development of artificial intelligence, parallel image processing is becoming an increasingly important ability of computing hardware. To meet the requirements of various image processing tasks,...
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Open AccessEngineered CRISPR/Cas9 enzymes improve discrimination by slowing DNA cleavage to allow release of off-target DNA
CRISPR/Cas9 is a programmable genome editing tool widely used for biological applications and engineered Cas9s have increased discrimination against off-target cleavage compared with wild-type Streptococcus py...
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Open AccessLocating induced earthquakes with a network of seismic stations in Oklahoma via a deep learning method
The accurate and automated determination of small earthquake (ML < 3.0) locations is still a challenging endeavor due to low signal-to-noise ratio in data. However, such information is critical for monitoring sei...
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Open AccessGamma Knife radiosurgery for cerebral cavernous malformation
This is a retrospective study examining the efficacy and safety of Gamma Knife radiosurgery (GKS) in treating patients with cerebral cavernous malformations (CCMs). Between 1993 and 2018, 261 patients with 331...
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Open AccessInvestigation on the adsorption of phosphorus in all fractions from sediment by modified maifanite
Sediment phosphorus (P) removal is crucial for the control of eutrophication, and the in-situ adsorption is an essential technique. In this study, modified maifanite (MMF) prepared by acidification, alkalization,...
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Open AccessThe preparation and application of a graphene-based hybrid flame retardant containing a long-chain phosphaphenanthrene
A novel hybrid flame retardant combining graphene oxide (GO) with long-chain phosphaphenanthrene was fabricated via surface grafting reaction. Taking advantageous of the double barrier effects, including the p...
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Open AccessAtomically informed nonlocal semi-discrete variational Peierls-Nabarro model for planar core dislocations
Prediction of Peierls stress associated with dislocation glide is of fundamental concern in understanding and designing the plasticity and mechanical properties of crystalline materials. Here, we develop a non...
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Open AccessStructural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity
Methyltransferases play crucial roles in many cellular processes, and various regulatory mechanisms have evolved to control their activities. For methyltransferases involved in biosynthetic pathways, regulatio...