8 Result(s)
within
**qiu Xu
Life Sciences, general
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Article
Open AccessCorrection: Novel insights into the METTL3-METTL14 complex in musculoskeletal diseases
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Article
Open AccessNovel insights into the METTL3-METTL14 complex in musculoskeletal diseases
N6-methyladenosine (m6A) modification, catalyzed by methyltransferase complexes (MTCs), plays many roles in multifaceted biological activities. As the most important subunit of MTCs, the METTL3-METTL14 complex is...
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Article
Open AccessTargeting mitochondrial one-carbon enzyme MTHFD2 together with pemetrexed confers therapeutic advantages in lung adenocarcinoma
Metabolic remodeling is the fundamental molecular feature of malignant tumors. Cancer cells require sufficient energy supplies supporting their high proliferative rate. MTHFD2, a mitochondrial one-carbon metab...
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Article
Open AccessCircular RNAs in osteoporosis: expression, functions and roles
Osteoporosis, which is caused by an imbalance in osteoblasts and osteoclasts, is a global age-related metabolic disease. Osteoblasts induce osteocyte and bone matrix formation, while osteoclasts play an import...
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Article
Open AccessAMPK activation by ASP4132 inhibits non-small cell lung cancer cell growth
Activation of adenosine monophosphate-activated protein kinase (AMPK) is able to produce significant anti-non-small cell lung cancer (NSCLC) cell activity. ASP4132 is an orally active and highly effective AMPK...
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Article
An Improved Group Decision-Making Model for the Investment Options of Small-Scale Photovoltaic Systems Based on Cumulative Prospect Theory and Choquet Integral
With the development of photovoltaic (PV) industry, installing small-scale PV systems which are integrated into the buildings becomes popular. Therefore, it is important to make optimal investment decisions fo...
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Article
Characterization of Clarias gariepinus mitochondrial genome sequence and a comparative analysis with other catfishes
Clarias gariepinus is an economically important fish belonging to Siluriformes. In order to understand the characterization of catfishes, the complete mitochondrial genome sequence of the African catfish C. garie...
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Article
A novel personalized Web search model
A novel personalized Web search model is proposed. The new system, as a middleware between a user and a Web search engine, is set up on the client machine. It can learn a user’s preference implicitly and then ...
