![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Open AccessRadiation-induced upregulation of FGL1 promotes esophageal squamous cell carcinoma metastasis via IMPDH1
While radiation therapy remains pivotal in esophageal squamous cell carcinoma (ESCC) treatment, the perplexing phenomenon of post-radiation metastasis presents a formidable clinical challenge. This study inves...
-
Article
Highly efficient solution-processed organic photovoltaics enabled by improving packing behavior of organic semiconductors
Solution processability is a unique property of organic semiconductors. The compact and regular π-π stacking between molecules is paramount in the performance of organic optoelectronic devices. However, it is ...
-
Article
RMSRM: real-time monitoring-based self-reconfiguration mechanism in reconfigurable PE array
Modern applications need to flexibly adjust the processing process according to the different environments and real-time processing, thus putting forward higher requirements for the reconfiguration performance...
-
Article
Optimization of adaptation parameters from adhesion cell culture in serum-containing media to suspension in chemically defined media by superlative box design
A new design of experiments—superlative box design (SBD), was adopted to optimize the adaptation of Chinese hamster ovary cells from adhesion culture to serum-free suspension culture. It is a general trend to ...
-
Article
Protein Multiple Conformation Prediction Using Multi-Objective Evolution Algorithm
The breakthrough of AlphaFold2 and the publication of AlphaFold DB represent a significant advance in the field of predicting static protein structures. However, AlphaFold2 models tend to represent a single st...
-
Article
Does the Construction of Transportation Infrastructure Enhance Regional Innovation Capabilities: Evidence from China
Based on the data of various provinces in China from 1996 to 2018, this article empirically tests the impact of transportation infrastructure on innovation capabilities. The empirical results show that the imp...
-
Article
Open AccessCD16 CAR-T cells enhance antitumor activity of CpG ODN-loaded nanoparticle-adjuvanted tumor antigen-derived vaccinevia ADCC approach
Combinatorial immunotherapy strategies for enhancing the responsiveness of immune system have shown great promise for cancer therapy. Engineered nanoformulation incorporated toll-like receptor (TLR) 9 agonist ...
-
Chapter and Conference Paper
Data Mining Series Experiment Design and OJ System Development Based on R Language
Based on a comprehensive analysis of the existing Online Judge (OJ) evaluation systems at home and abroad, this paper designs and implements a new R language data mining online evaluation system based on HUSTO...
-
Chapter and Conference Paper
Research on an Evaluation System of Individual Digitalization Capability
The surge of digital economy will break the traditional business models, the way companies interact, and the way people obtain services, information and commodities, thereby changing the way people live. With ...
-
Article
Does the Internet trigger an innovative spatial revolution: evidence from China
This paper uses panel data from 30 provinces in China from 2006 to 2018 to empirically test the influence of the Internet on the innovation gap between regions. Contrary to our intuition, the test results show...
-
Article
A molecularly imprinted electrochemical aptasensor based on zinc oxide and co-deposited gold nanoparticles/reduced graphene oxide composite for detection of amoxicillin
The molecularly imprinted electrochemical aptasensor was constructed based on co-deposition of zinc oxide and gold nanoparticles/reduced graphene oxide composite. Aptamer was used as a new kind of functional m...
-
Article
Open AccessSerum albumin and the short-term mortality in individuals with congestive heart failure in intensive care unit: an analysis of MIMIC
Decreased albumin levels are common in congestive heart failure (CHF), but little is known about its role in mortality risk in CHF. This study developed a cohort prediction model based on 7121 individuals with...
-
Article
A FRET Fluorescent Sensor for Ratiometric and Visual Detection of Sulfide Based on Carbon Dots and Silver Nanoclusters
In this work, the fluorescent sensor based on fluorescence resonance energy transfer (FRET) and electrostatic interaction (EI) was prepared for the ratiometric and visual detecting S2–. The FRET fluorescent senso...
-
Article
Determination of water in organic solvents and raw food products by fluorescence quenching of a crystalline vinyl-functionalized COF
Covalent organic frameworks (COFs) with good chemical stability, flexible chemical functionalization, tunable pore sizes, and high specific surface areas have been increasingly employed in the field of fluores...
-
Article
Open AccessBoosting nutrient starvation-dominated cancer therapy through curcumin-augmented mitochondrial Ca2+ overload and obatoclax-mediated autophagy inhibition as supported by a novel nano-modulator GO-Alg@CaP/CO
By hindering energy supply pathway for cancer cells, an alternative therapeutic strategy modality is put forward: tumor starvation therapy. And yet only in this blockade of glucose supply which is far from eno...
-
Article
A Significant Fluorescent Aptamer Sensor Based on Carbon Dots and Graphene Oxide for Highly Selective Detection of Progesterone
In this paper, a fluorescent aptamer sensor was constructed based on the carbon dots (CDs) and graphene oxide (GO). This sensor combines the excellent fluorescence performance of CDs with the high specificity ...
-
Article
Near-infrared carbon dots for cell imaging and detecting ciprofloxacin by label-free fluorescence sensor based on aptamer
A label-free fluorescence sensor based on near-infrared carbon dots (NIR-CDs) and aptamer is described for the highly sensitive and selective detection of ciprofloxacin (CIP). NIR-CDs were synthesized from pol...
-
Article
Open AccessSelf-assembled fluorescent hybrid nanoparticles-mediated collaborative lncRNA CCAT1 silencing and curcumin delivery for synchronous colorectal cancer theranostics
Cancer synergistic therapy strategy in combination with therapeutic gene and small molecule drug offers the possibility to amplify anticancer efficiency. Colon cancer-associated transcript-1 (CCAT1) is a well ...
-
Article
Open AccessEffects of different sodium salts and nitrogen sources on the production of 3-hydroxybutyrate and polyhydroxybutyrate by Burkholderia cepacia
The effects of NaCl, Na2SO4, Na2HPO4, and Na3C6H5O7 on the production of 3-hydroxybutyrate, polyhydroxybutyrate, and by-products by Burkholderia cepacia. Proper addition of Na3C6H5O7 can significantly promote the...
-
Article
Development of highly efficient and reusable magnetic nitrogen-doped carbon nanotubes for chlorophenol removal
Nitrogen-doped carbon nanotubes (N-CNTs) were synthesized via a hydrothermal method and further modified with magnetic Co0.5Cu0.5Fe2O4 nanoparticles following a one-pot solvothermal method. The characterization d...