410 Result(s)
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Article
Open AccessChiral plasmonics of self-assembled nanorod dimers
Chiral nanoscale photonic systems typically follow either tetrahedral or helical geometries that require four or more different constituent nanoparticles. Smaller number of particles and different chiral geome...
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Article
Correction: Corrigendum: The tRNA methyltransferase NSun2 stabilizes p16INK4 mRNA by methylating the 3′-untranslated region of p16
Nature Communications 3: Article number: 712 (2012); Published: 6 March 2012; Updated: 25 October 2013. Concern was raised over the level of processing of the images in Fig. 2b in this Article. Because the ori...
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Open AccessPhotoluminescence of a single complex plasmonic nanoparticle
We report detailed investigations of the photoluminescence (PL) generated from an individual gold nanoflower, a highly branched plasmonic nanoparticle. Compared to nanostructures with simple shapes, such as sp...
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Open AccessChromosomal DNA deletion confers phage resistance to Pseudomonas aeruginosa
Bacteria develop a broad range of phage resistance mechanisms, such as prevention of phage adsorption and CRISPR/Cas system, to survive phage predation. In this study, Pseudomonas aeruginosa PA1 strain was infect...
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Open AccessThree-dimensional Printed Acrylonitrile Butadiene Styrene Framework Coated with Cu-BTC Metal-organic Frameworks for the Removal of Methylene Blue
Three-dimensional (3D) printing was applied for the fabrication of acrylonitrile butadiene styrene (ABS) framework. Functionalization of the ABS framework was then performed by coating of porous Cu-BTC (BTC = ...
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Open AccessSingle Molecule Investigation of Ag+ Interactions with Single Cytosine-, Methylcytosine- and Hydroxymethylcytosine-Cytosine Mismatches in a Nanopore
Both cytosine-Ag-cytosine interactions and cytosine modifications in a DNA duplex have attracted great interest for research. Cytosine (C) modifications such as methylcytosine (mC) and hydroxymethylcytosine (h...
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Open AccessCassava genome from a wild ancestor to cultivated varieties
Cassava is a major tropical food crop in the Euphorbiaceae family that has high carbohydrate production potential and adaptability to diverse environments. Here we present the draft genome sequences of a wild ...
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Open AccessMolecular evolution and functional divergence of tubulin superfamily in the fungal tree of life
Microtubules are essential for various cellular activities and β-tubulins are the target of benzimidazole fungicides. However, the evolution and molecular mechanisms driving functional diversification in funga...
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Open AccessGPR39 marks specific cells within the sebaceous gland and contributes to skin wound healing
G protein-coupled receptors (GPCRs) mediate multiple key biological processes in the body. The orphan receptor GPR39 has been reported to be involved in various pathophysiological events. However, the function...
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Open AccessPathway and kinetics of cyhalothrin biodegradation by Bacillus thuringiensis strain ZS-19
Cyhalothrin is a common environmental pollutant which poses increased risks to non-target organisms including human beings. This study reported for the first time a newly isolated strain, Bacillus thuringiensis Z...
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Open AccessIsolation and characterization of a native avirulent strain of Streptococcus suis serotype 2: a perspective for vaccine development
Streptococcus suis, an emerging infectious pathogen, is the cause of two large-scale outbreaks of human streptococcal toxic shock syndrome in China and has attracted much attention from the scientific community. ...
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Open AccessThe decomposition of fine and coarse roots: their global patterns and controlling factors
Fine root decomposition represents a large carbon (C) cost to plants and serves as a potential soil C source, as well as a substantial proportion of net primary productivity. Coarse roots differ markedly from ...
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Open AccessTargeting blood thrombogenicity precipitates atherothrombotic events in a mouse model of plaque destabilization
Although some features of plaque instability can be observed in genetically modified mouse models, atherothrombosis induction in mice has been attested to be difficult. We sought to test the hypothesis that al...
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Open AccessHIV burden in men who have sex with men: a prospective cohort study 2007–2012
We conducted a prospective cohort study among HIV-negative MSM aged 18 years or older between 2007 and 2012 in Bei**g, China to measure the rates of incident HIV and identify risk factors for infection. Among...
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Article
Open AccessKindlin-2 controls TGF-β signalling and Sox9 expression to regulate chondrogenesis
The signals that control skeletogenesis are incompletely understood. Here we show that deleting Kindlin-2 in Prx1-expressing mesenchymal progenitors in mice causes neonatal lethality, chondrodysplasia and loss...
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Correction: Corrigendum: Single Molecule Investigation of Ag+ Interactions with Single Cytosine-, Methylcytosine- and Hydroxymethylcytosine-Cytosine Mismatches in a Nanopore
Both cytosine-Ag-cytosine interactions and cytosine modifications in a DNA duplex have attracted great interest for research. Cytosine (C) modifications such as methylcytosine (mC) and hydroxymethylcytosine (h...
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Article
Open AccessProgeny Clustering: A Method to Identify Biological Phenotypes
Estimating the optimal number of clusters is a major challenge in applying cluster analysis to any type of dataset, especially to biomedical datasets, which are high-dimensional and complex. Here, we introduce...
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Open AccessChronic inflammation up-regulates P-gp in peripheral mononuclear blood cells via the STAT3/Nf-κb pathway in 2,4,6-trinitrobenzene sulfonic acid-induced colitis mice
Patients with inflammatory bowel diseases, including Crohn’s disease and ulcerative colitis, often suffer drug intolerance. This resistance can be divided into intrinsic resistance and acquired resistance. Alt...
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Open AccessUnprecedented reactions: from epichlorohydrin to epoxyglycidyl substituted divinyl ether and its conversion into epoxyglycidyl propargyl ether
The reaction of epichlorohydrin with concentrated sodium hydroxide in hexane under phase transfer conditions has surprisingly led to the formation of the symmetrical di(3-epoxyglycidyl-1-propenyl) ether 1 which c...
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Open AccessEvaluation of regulatory genetic variants in POU5F1 and risk of congenital heart disease in Han Chinese
OCT4 is a transcription factor of the POU family, which plays a key role in embryonic development and stem cell pluripotency. Previous studies have shown that Oct4 is required for cardiomyocyte differentiation...
