856 Result(s)
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Article
A review on nanofiber-based composites for toxic and flammable gas sensing
Nanofibers, due to the characteristics of high porosity, large specific surface area, and high strength and mechanical flexibility, exhibit a great potential for gas sensing as a sensing layer or versatile sup...
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Open AccessLongitudinal metabolomics of human plasma reveal metabolic dynamics and predictive markers of antituberculosis drug-induced liver injury
Tuberculosis (TB) remains the second leading cause of death from a single infectious agent and long-term medication could lead to antituberculosis drug-induced liver injury (ATB-DILI). We established a prospec...
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Article
A modified method for isolating sinoatrial node myocytes from adult mice
Sinoatrial node (SAN) is the pacemaker of the heart in charge of initiating spontaneous electronical activity and controlling heart rate. Myocytes from SAN can generate spontaneous rhythmic action potentials, ...
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Open AccessThe impact of virtual reality on practical skills for students in science and engineering education: a meta-analysis
Virtual reality (VR) has emerged as a promising tool for enhancing practical skills of students in science and engineering education. However, the effectiveness of VR in this context remains unclear due to inc...
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Article
Validating the use of ROS-scavenging bacteria as probiotics to increase coral resilience to thermal stress
Thermal stress causes the overproduction and toxic accumulation of reactive oxygen species (ROS), which seems to be correlated with coral bleaching and, ultimately, death. The reduction of ROS concentration wi...
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Analysis of chitinase gene family in barley and function study of HvChi22 involved in drought tolerance
Chitinase (Chi) is a pathogenesis-related protein, also reported to play an important role in plant responses to abiotic stress. However, its role in response to abiotic stress in barley is still unclear.
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Article
Open AccessMicrobial imbalance in Chinese children with diarrhea or constipation
Diarrhea and constipation are common health concerns in children. Numerous studies have identified strong association between gut microbiota and digestive-related diseases. But little is known about the gut mi...
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Open AccessModeling of distortional hardening including plane strain tension and pure shear for a TWIP steel
This paper focuses on calibrating and modeling of distortional hardening behaviours in twinning induced plasticity steels. True stress-strain curves for uniaxial tension, plane strain tension, and pure shear s...
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Article
Open AccessThe Mutual Regulatory Role of Ferroptosis and Immunotherapy in Anti-tumor Therapy
Ferroptosis is a form of cell death that is triggered by the presence of ferrous ions and is characterized by lipid peroxidation induced by these ions. The mechanism exhibits distinct morphological characteris...
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Article
The wall-associated kinase GWN1 controls grain weight and grain number in rice
Grain size is a crucial agronomic trait that determines grain weight and final yield. Although several genes have been reported to regulate grain size in rice (Oryza sativa), the function of Wall-Associated Kinas...
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Article
Dietary intakes of vitamin D promote growth performance and disease resistance in juvenile grass carp (Ctenopharyngodon idella)
Vitamin D3 (VD3) is an essential nutrient for fish and participates in a variety of physiological activities. Notably, both insufficient and excessive supplementation of VD3 severely impede fish growth, and the r...
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Article
Development and application of the TRV-induced gene-silencing system in different Rhododendron species
Rhododendron is one of the top ten traditional flowers in China, with high ornamental and medicinal values. However, molecular research on this species has been impeded by the lack of efficient molecular genetic ...
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Open AccessA potent Henipavirus cross-neutralizing antibody reveals a dynamic fusion-triggering pattern of the G-tetramer
The Hendra and Nipah viruses (HNVs) are highly pathogenic pathogens without approved interventions for human use. In addition, the interaction pattern between the attachment (G) and fusion (F) glycoproteins re...
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Open AccessAssociations between chronic obstructive pulmonary disease and ten common cancers: novel insights from Mendelian randomization analyses
Chronic obstructive pulmonary disease (COPD) is a significant global health issue, suspected to elevate the risk for various cancers. This study sought to discern whether COPD serves as a risk marker or a caus...
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Article
Open AccessDe novo transcriptome assembly database for 100 tissues from each of seven species of domestic herbivore
Domesticated herbivores are an important agricultural resource that play a critical role in global food security, particularly as they can adapt to varied environments, including marginal lands. An understandi...
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Article
Lycopene promoted M2 macrophage polarization via inhibition of NOTCH1-PI3K-mTOR-NF-κB-JMJD3-IRF4 pathway in response to Escherichia coli infection in J744A.1 cells
Escherichia coli (E. coli) can induce severe clinical bovine mastitis, which is to blame for large losses experienced by dairy farms. Macrophage polarization into various states is in response to pathogen infecti...
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Open AccessCombination therapy with oncolytic virus and T cells or mRNA vaccine amplifies antitumor effects
Antitumor therapies based on adoptively transferred T cells or oncolytic viruses have made significant progress in recent years, but the limited efficiency of their infiltration into solid tumors makes it diff...
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Open AccessRelationship between socioeconomic status and hypertension incidence among adults in southwest China: a population-based cohort study
To investigate the correlation between socioeconomic status (SES) and the incidence of hypertension among adults aged 18 or above in southwest China.
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Article
Seasonal changes in gut microbiota of sea cucumber over natural aestivation cycle
Sea cucumber Apostichopus japonicus is an ideal model organism for marine invertebrate aestivation; it annually enters a “slee** state” for nearly 3 months when ambient water temperature range is 25–30 °C. The ...
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Article
Open AccessUnmet Needs and Treatment Preference of Systemic Treatments for Moderate-to-Severe Psoriasis from the Perspectives of Patients and Dermatologists in China
The treatment options for moderate to severe psoriasis (msPsO) in China have been greatly increased with the approvals of biologics. However, the unmet needs and treatment preferences of systemic treatments fo...