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Article
Phosphorylation of USP27X by PIM2 promotes glycolysis and breast cancer progression via deubiquitylation of MYC
Aberrant cell proliferation is a hallmark of cancer, including breast cancer. Here, we show that USP27X is required for cell proliferation and tumorigenesis in breast cancer. We identify a PIM2-USP27X regulato...
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Article
Open AccessCorrection: Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis
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Article
Open AccessImport of digital products and production fragmentation
Empowering traditional manufacturing through the digital economy can not only enhance the competitiveness of Chinese manufacturing enterprises, but also enhance the degree of specialization of enterprises by o...
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Article
Arginine methylation of ALKBH5 by PRMT6 promotes breast tumorigenesis via LDHA-mediated glycolysis
ALKBH5 is a master regulator of N6-methyladenosine (m6A) modification, which plays a crucial role in many biological processes. Here, we show that ALKBH5 is required for breast tumor growth. Interestingly, PRMT6 ...
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Article
Professional commitment matters! linking employee strengths use to organizational citizenship behavior
This study aimed to examine the mediating role of professional commitment and the moderating role of role overload in the employee strengths use (ESU) and organizational citizenship behavior (OCB) relation. A ...
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Chapter and Conference Paper
Design of Hospital Equipment Information Management System Based on Computer Vision Technology
The information management of medical equipment should reflect two movement states of medical equipment, namely material movement state and value movement state, so that managers, decision makers, and users ca...
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Chapter and Conference Paper
Research on Digital Maturity Evaluation Model of Public Hospitals
Building an evaluation model of digital maturity in public hospitals, combining the data management maturity model with the digital maturity model, evaluating the research progress of digital transformation in...
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Article
Open AccessPhylogeny and molecular evolution of the first local monkeypox virus cluster in Guangdong Province, China
The first local mpox outbreak in Guangdong Province, China occurred in June 2023. However, epidemiological data have failed to quickly identify the source and transmission of the outbreak. Here, phylogeny and ...
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Article
Open AccessAssociation between serum uric acid and homocysteine levels among adults in the United States: a cross-sectional study
Many studies have shown that both elevated serum uric acid (SUA) levels and hyperhomocysteinemia are risk factors for atherosclerosis. However, the relationship between the two has not been thoroughly investig...
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Article
Open AccessHealthy lifestyle scores associate with incidence of type 2 diabetes mediated by uric acid
Whether and to what extent serum uric acid (SUA) mediates the association between combined lifestyle behaviors and type 2 diabetes mellitus (T2DM) remain unclear. This study aimed to investigate the role of SU...
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Article
Application value of CT-guided localization using a coil in combination with medical adhesive in sublobar resection
To explore the application value of CT-guided localization using a coil in combination with medical adhesive in sublobar resection.
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Article
PIM2 Promotes the Development of Ovarian Endometriosis by Enhancing Glycolysis and Fibrosis
Endometriosis is a common gynecological disorder characterized by the presence of the endometrial glands and the stroma outside the uterine cavity. The disease affects reproductive function and quality of life...
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Article
FDX1 enhances endometriosis cell cuproptosis via G6PD-mediated redox homeostasis
Cuproptosis is a new form of programmed cell death, which is associated with the mitochondrial TCA (tricarboxylic acid) cycle. But the functions of cuproptosis in endometriosis progression are still unknown. H...
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Article
Correction to: Multibranch multilevel federated learning for a better feature extraction and a plug-and-play dynamic-adjusting double flow personalization approach
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Article
Multibranch multilevel federated learning for a better feature extraction and a plug-and-play dynamic-adjusting double flow personalization approach
Federated learning (FL) is an emerging technique used to preserve the privacy of users’ data in training by a distributed machine learning approach. Previously, a client-edge-cloud hierarchical federated learn...
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Article
Open AccessQuantification of host proteomic responses to genotype 4 hepatitis E virus replication facilitated by pregnancy serum
Hepatitis E virus (HEV) infection is a common cause of acute hepatitis worldwide and causes approximately 30% case fatality rate among pregnant women. Pregnancy serum (PS), which contains a high concentration ...
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Article
Research on the preparation and property of superhydrophobic surface with micro-nano ripple structure
Superhydrophobic surfaces are widely used in various fields because of their excellent properties and are currently an important research hotspot. Here, we developed a simple method and successfully prepared a...
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Article
Open AccessAn mRNA-based T-cell-inducing antigen strengthens COVID-19 vaccine against SARS-CoV-2 variants
Herd immunity achieved through mass vaccination is an effective approach to prevent contagious diseases. Nonetheless, emerging SARS-CoV-2 variants with frequent mutations largely evaded humoral immunity induce...
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Article
Correction: CHIP induces ubiquitination and degradation of HMGB1 to regulate glycolysis in ovarian endometriosis
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Article
Implantation underneath the abdominal anterior rectus sheath enables effective and functional engraftment of stem-cell-derived islets
Human pluripotent stem cell-derived islets (hPSC islets) are a promising alternative to primary human islets for the treatment of insulin-deficient diabetes. We previously demonstrated the feasibility of this ...
