32 Result(s)
within
**ngrui Zhang
Life Sciences
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Article
Open AccessNatural variation of domestication-related genes contributed to latitudinal expansion and adaptation in soybean
Soybean is a major source of protein and edible oil worldwide. Originating from the Huang-Huai-Hai region, which has a temperate climate, soybean has adapted to a wide latitudinal gradient across China. Howeve...
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Article
Enhancing forest insect outbreak detection by integrating tree-ring and climate variables
Annual tree rings are widely recognized as valuable tools for quantifying and reconstructing historical forest disturbances. However, the influence of climate can complicate the detection of disturbance signal...
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Article
Biocontrol potential of plant growth-promoting rhizobacteria against plant disease and insect pest
Biological control is a promising approach to enhance pathogen and pest control to ensure high productivity in cash crop production. Therefore, PGPR biofertilizers are very suitable for application in the cult...
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Article
Hemin blocks TIGIT/PVR interaction and induces ferroptosis to elicit synergistic effects of cancer immunotherapy
The immune checkpoint TIGIT/PVR blockade exhibits significant antitumor effects through activation of NK and CD8+ T cell-mediated cytotoxicity. Immune checkpoint blockade (ICB) could induce tumor ferroptosis thro...
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Article
A new method of calculating crown projection area and its comparative accuracy with conventional calculations for asymmetric tree crowns
This paper introduces a new method of calculating crown projection area (CPA), the area of level ground covered by a vertical projection of a tree crown from measured crown radii through numerical interpolation a...
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Article
Open AccessIdentification of the principal neuropeptide MIP and its action pathway in larval settlement of the echiuran worm Urechis unicinctus
Larval settlement and metamorphosis represent critical events in the life history of marine benthic animals. Myoinhibitory peptide (MIP) plays a pivotal role in larval settlement of marine invertebrates. Howev...
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Open AccessDiscovery of a novel small molecule as CD47/SIRPα and PD-1/PD-L1 dual inhibitor for cancer immunotherapy
Targeting the tumor microenvironment (TME) has emerged as a promising strategy in cancer treatment, particularly through the utilization of immune checkpoint blockade (ICB) agents such as PD-1/PD-L1 inhibitors...
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Article
The study of the mechanism of non-coding RNA regulation of programmed cell death in diabetic cardiomyopathy
Diabetic cardiomyopathy (DCM) represents a distinct myocardial disorder elicited by diabetes mellitus, characterized by aberrations in myocardial function and structural integrity. This pathological condition ...
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Open AccessMaize heat shock proteins—prospection, validation, categorization and in silico analysis of the different ZmHSP families
Among the plant molecular mechanisms capable of effectively mitigating the effects of adverse weather conditions, the heat shock proteins (HSPs), a group of chaperones with multiple functions, stand out. At a ...
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Article
Combining surface-accessible Ag and Au colloidal nanomaterials with SERS for in situ analysis of molecule–metal interactions in complex solution environments
The interactions between molecules and noble metal nanosurfaces play a central role in many areas of nanotechnology. The surface chemistry of noble metal surfaces under ideal, clean conditions has been extensi...
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Article
MiR-601-induced BMSCs senescence accelerates steroid-induced osteonecrosis of the femoral head progression by targeting SIRT1
The imbalance between osteogenic and adipogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) is not only the primary pathological feature but also a major contributor to the pathogenesis of st...
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Article
Open AccessExtant thrips diverged in the early tertiary period
Thysanoptera, commonly known as thrips, are diverse tiny insects whose earliest fossil record dates back to the Triassic period. Since there are few studies on the divergence time of taxa under Thysanoptera, t...
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Article
Identification of quantitative trait loci and candidate genes for seed folate content in soybean
From 61 QTL mapped, a stable QTL cluster of 992 kb was discovered on chromosome 5 for folate content and a putative candidate gene, Glyma.05G237500, was identified.
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Article
Identification of genes for seed isoflavones based on bulk segregant analysis sequencing in soybean natural population
We identified four hub genes for isoflavone biosynthesis based on BSA-seq and WGCNA methods and validated that GmIE3-1 positively contribute to isoflavone accumulation in soybean.
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Protocol
Characterization of Deubiquitinase Catalytic State Using a Structure-Based Approach
The activity of deubiquitinases (DUBs) is tightly regulated in eukaryotes via various mechanisms. One of the regulatory strategies is substrate-induced catalytic triad rearrangement, where ubiquitin-binding he...
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Article
Open AccessLINC01123 promotes immune escape by sponging miR-214-3p to regulate B7–H3 in head and neck squamous-cell carcinoma
Numerous studies have shown that long noncoding RNAs (LncRNAs) are involved in the development and immune escape of head and neck squamous-cell carcinoma (HNSCC). However, the specific regulatory mechanisms by...
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Article
Effects of dietary supplementation with alpha-lipoic acid on apparent digestibility and serum metabolome alterations of sheep in summer
To investigate the effects of alpha-lipoic acid (LA) on the nutrition metabolism of sheep (36.72 ± 1.44 kg) in the summer, twenty-one sheep were randomly assigned to three treatments addressing LA supplementat...
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Article
Proteomic Analysis of the Responses to Co-Stimulation of Intestinal Aeromonas and Shewanella in Lamprey Leukocytes
Lamprey, one of the most basal jawless vertebrate, is an excellent model for studying vertebrate evolution, embryo development, and the origin of adaptive immunity. This study investigated the differentially e...
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Article
Open AccessEcological and network analyses identify four microbial species with potential significance for the diagnosis/treatment of ulcerative colitis (UC)
Ulcerative colitis (UC) is one of the primary types of inflammatory bowel disease (IBD), the occurrence of which has been increasing worldwide. Although IBD is an intensively studied human microbiome-associate...
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Article
Simultaneous application of entomopathogenic Beauveria bassiana granules and predatory mites Stratiolaelaps scimitus for control of western flower thrips, Frankliniella occidentalis
Western flower thrips, F. occidentalis (Pergande) (Thysanoptera: Thripidae), is one of the most important pests of agricultural and horticultural crops worldwide. Adults and larvae injure plants through their fee...
