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First-in-human validation of enzymolysis clearance strategy for decreasing renal radioactivity using modified [68Ga]Ga-HER2 Affibody

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  1. Article

    Open Access

    Serum Elabela expression is decreased in hypertensive patients and could be associated with the progression of hypertensive renal damage

    Elabela, a recently discovered hormonal peptide containing 32 amino acids, is a ligand for the apelin receptor. It can lower blood pressure and attenuate renal fibrosis. However, the clinicopathological relati...

    Geng Tian, Qian Zheng, Qingru Zhang, **aoyu Liu in European Journal of Medical Research (2024)

  2. Article

    Open Access

    Inhibition of the m6A reader IGF2BP2 as a strategy against T-cell acute lymphoblastic leukemia

    T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignant leukemia with extremely limited treatment for relapsed patients. N6‐methyladenosine (m6A) reader insulin-like growth factor 2 mRNA-binding pr...

    Panpan Feng, Dawei Chen, **a Wang, Yanxia Li, Zhenyu Li, Boya Li, Yupeng Zhang in Leukemia (2022)

  3. Article

    Open Access

    Safety and efficacy of meplazumab in healthy volunteers and COVID-19 patients: a randomized phase 1 and an exploratory phase 2 trial

    Recent evidence suggests that CD147 serves as a novel receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Blocking CD147 via anti-CD147 antibody could suppress the in vitro SAR...

    Huijie Bian, Zhao-Hui Zheng, Ding Wei in Signal Transduction and Targeted Therapy (2021)

  4. Article

    Open Access

    Early BCR-ABL1 decline in imatinib-treated patients with chronic myeloid leukemia: results from a multicenter study of the Chinese CML alliance

    An early molecular response is spectacularly predictive of outcome in chronic myeloid leukemia (CML) and early response landmarks may identify the high-risk patients likely to be benefit from an early therapy ...

    **gru Zhang, Yingqiao Wang, Jianxiang Wang, Jianda Hu, Suning Chen in Blood Cancer Journal (2018)

  5. Article

    Open Access

    Wnt signaling is involved in 6-benzylthioinosine-induced AML cell differentiation

    We previously demonstrated that 6-benzylthioinosine (6-BT) could induce the differentiation of a subset of acute myeloid leukemia (AML) cell lines and primary AML cells regardless of their cytogenetics. In thi...

    Shaolei Zang, Na Liu, Hongchun Wang, David N Wald, Na Shao, **gru Zhang in BMC Cancer (2014)

  6. Article

    Open Access

    Radiation recall pneumonitis induced by chemotherapy after thoracic radiotherapy for lung cancer

    Radiation recall pneumonitis (RRP) describes a rare reaction in previously irradiated area of pulmonary tissue after application of triggering agents. RRP remains loosely characterized and poorly understood si...

    **ao Ding, Wei Ji, Junling Li, **angru Zhang, Luhua Wang in Radiation Oncology (2011)