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Open AccessCorrection: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
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Open AccessCorrection: CREBZF mRNA nanoparticles suppress breast cancer progression through a positive feedback loop boosted by circPAPD4
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Open AccessCREBZF mRNA nanoparticles suppress breast cancer progression through a positive feedback loop boosted by circPAPD4
Breast cancer (BC) negatively impacts the health of women worldwide. Circular RNAs (circRNAs) are a group of endogenous RNAs considered essential regulatory factor in BC tumorigenesis and progression. However,...
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Article
Open AccessThe prognostic value of the advanced lung cancer inflammation index in patients with gastrointestinal malignancy
Systemic inflammation is crucial for the development and progression of cancers. The advanced lung cancer inflammation index (ALI) is considered to be a better indicator of systemic inflammation than current b...
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Article
Open AccessCorrection to: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
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Article
Open AccessKetogenic diet alleviates colitis by reduction of colonic group 3 innate lymphoid cells through altering gut microbiome
Accumulating evidence suggests that ketogenic diets (KDs) mediate the rise of circulating ketone bodies and exert a potential anti-inflammatory effect; however, the consequences of this unique diet on colitis ...
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Article
Open AccessDiscovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
Non-small cell lung cancer (NSCLC) patients with activating EGFR mutations initially respond to first-generation EGFR inhibitors; however, the efficacy of these drugs is limited by acquired resistance driven b...
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Article
Open AccessExosome-mediated transfer of miR-93-5p from cancer-associated fibroblasts confer radioresistance in colorectal cancer cells by downregulating FOXA1 and upregulating TGFB3
Cancer-associated fibroblasts (CAFs) have been intensively studied in recent studies with aims of finding more concrete evidence on their mechanism of involvement in tumor progression, which is currently unkno...
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Open AccessLimb ischemic preconditioning ameliorates renal microcirculation through activation of PI3K/Akt/eNOS signaling pathway after acute kidney injury
Contrast-induced acute kidney injury (CI-AKI) resulting from administration of iodinated contrast media (CM) is the third leading cause of hospital-acquired acute kidney injury and is associated with substanti...
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Open AccessThe transcription factor FOXO4 is down-regulated and inhibits tumor proliferation and metastasis in gastric cancer
FOXO4, a member of the FOXO family of transcription factors, is currently the focus of intense study. Its role and function in gastric cancer have not been fully elucidated. The present study was aimed to inve...