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Author Correction: A dual-targeting antifungal is effective against multidrug-resistant human fungal pathogens
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Open AccessDe novo genome assembly of a high-protein soybean variety HJ117
Soybean is an important feed and oil crop in the world due to its high protein and oil content. China has a collection of more than 43,000 soybean germplasm resources, which provides a rich genetic diversity f...
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Author Correction: Metagenomic and metabolomic remodeling in nonagenarians and centenarians and its association with genetic and socioeconomic factors
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Open AccessFrameshift and wild-type proteins are often highly similar because the genetic code and genomes were optimized for frameshift tolerance
Frameshift mutations have been considered of significant importance for the molecular evolution of proteins and their coding genes, while frameshift protein sequences encoded in the alternative reading frames ...
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Open AccessLong non-coding RNA HOTAIR knockdown enhances radiosensitivity through regulating microRNA-93/ATG12 axis in colorectal cancer
Colorectal cancer (CRC) is a global healthcare problem. Radioresistance is a huge setback for CRC radiotherapy. In this text, the roles and molecular mechanisms of long non-coding RNA HOTAIR in CRC tumorigenes...
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Open AccessPristimerin induces apoptosis and autophagy via activation of ROS/ASK1/JNK pathway in human breast cancer in vitro and in vivo
Breast cancer is the most common malignant tumor in women, and progress toward long-term survival has stagnated. Pristimerin, a natural quinonemethide triterpenoid, exhibits potential anti-tumor effects on var...
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Author Correction: Nitrate–NRT1.1B–SPX4 cascade integrates nitrogen and phosphorus signalling networks in plants
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Open AccessRegulation of mATG9 trafficking by Src- and ULK1-mediated phosphorylation in basal and starvation-induced autophagy
Autophagy requires diverse membrane sources and involves membrane trafficking of mATG9, the only membrane protein in the ATG family. However, the molecular regulation of mATG9 trafficking for autophagy initiat...
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Open AccessAn integrative and applicable phylogenetic footprinting framework for cis-regulatory motifs identification in prokaryotic genomes
Phylogenetic footprinting is an important computational technique for identifying cis-regulatory motifs in orthologous regulatory regions from multiple genomes, as motifs tend to evolve slower than their surround...
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Open AccessRevisiting operons: an analysis of the landscape of transcriptional units in E. coli
Bacterial operons are considerably more complex than what were thought. At least their components are dynamically rather than statically defined as previously assumed. Here we present a computational study of ...
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Coupled natural and human systems: a landscape ecology perspective