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Article
Open AccessKnowledge of Alzheimer’s disease and associated factors among adults in Zhuhai, China: a cross-sectional analysis
This study aimed to assess the public knowledge regarding Alzheimer’s Disease (AD) in Zhuhai, China, focusing on identifying knowledge gaps and the influence of demographic and health factors.
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Article
Clinical implications of CSF-ctDNA positivity in newly diagnosed diffuse large B cell lymphoma
The clinical implications of CSF-ctDNA positivity in newly diagnosed diffuse large B cell lymphoma (ND-DLBCL) remains largely unexplored. One hundred ND-DLBCL patients were consecutively enrolled as training c...
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Article
A global survey on the use of the international classification of diseases codes for metabolic dysfunction-associated fatty liver disease
With the implementation of the 11th edition of the International Classification of Diseases (ICD-11) and the publication of the metabolic dysfunction-associated fatty liver disease (MAFLD) nomenclature in 2020...
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Article
Open AccessNatural variation in BnaA07.MKK9 confers resistance to Sclerotinia stem rot in oilseed rape
Sclerotinia stem rot (SSR), caused by the necrotrophic fungus Sclerotinia sclerotiorum, is one of the most devastating diseases for several major oil-producing crops. Despite its impact, the genetic basis of SSR ...
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Article
Angiotensin II type-2 receptor signaling facilitates liver injury repair and regeneration via inactivation of Hippo pathway
The angiotensin II type 2 receptor (AT2R) is a well-established component of the renin-angiotensin system and is known to counteract classical activation of this system and protect against organ damage. Pharma...
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Article
The magmatic origin of propylitic alteration of the Zhengguang epithermal Au-Zn deposit, Heilongjiang, China: evidence from mineral compositions and H–O-Sr isotopes
The origin of propylitic fluids in intermediate sulfidation mineralization has not been investigated in detail. Here, we present an extensive petrographic, geochemical, and isotopic (O-H-Sr) study of propyliti...
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Article
CircNSD1 promotes cardiac fibrosis through targeting the miR-429-3p/SULF1/Wnt/β-catenin signaling pathway
Cardiac fibrosis is a detrimental pathological process, which constitutes the key factor for adverse cardiac structural remodeling leading to heart failure and other critical conditions. Circular RNAs (circRNA...
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Article
Anomalous thermal expansion and enhanced magnetocaloric effect in <001>-textured MnxFe5–xSi3 alloys
The development of zero and negative thermal expansion (i.e., ZTE and NTE) materials is of crucial importance to the control of undesirable thermal expansion for high-precision devices. In the present work, ZT...
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Article
Corrosion behavior of as-cast Al0.75CoFeCr1.25Ni high entropy alloy in 0.5 mol/L NaOH solution
The corrosion behavior of an Al0.75CoFeCr1.25Ni high-entropy alloy (HEA) in 0.5 mol/L NaOH solution was investigated using a series of electrochemical and analytical techniques, including X-ray photoelectron spec...
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Article
The field-scale stabilization remediation and assessment of potential toxic elements based on the multi-source information from a Chinese Pb/Zn smelter contaminated site
Potential toxic elements (PTEs) generally co-existing in soils make a great challenge to the sustainable development and utilization of smelter contaminated sites. This study delved into the pollution characte...
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Article
Tricarboxylic acid cycle metabolites: new players in macrophage
Metabolic remodeling is a key feature of macrophage activation and polarization. Recent studies have demonstrated the role of tricarboxylic acid (TCA) cycle metabolites in the innate immune system. In the curr...
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Article
Open AccessMiRNA-296-5p promotes the sensitivity of nasopharyngeal carcinoma cells to cisplatin via targeted inhibition of STAT3/KLF4 signaling axis
Improving drug sensitivity is an important strategy in chemotherapy of cancer and accumulating evidence indicates that miRNAs are involved in the regulation of drug sensitivity, but the specific mechanism is s...
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Article
Fanconi Anemia Complementary Group A (FANCA) Facilitates the Occurrence and Progression of Liver Hepatocellular Carcinoma
Liver hepatocellular carcinoma (LIHC) is a serious liver disease worldwide, and its pathogenesis is complicated.
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Article
Diagnosis, treatment and prevention of severe acute respiratory syndrome coronavirus 2 infection in children: experts’ consensus statement updated for the Omicron variant
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Article
Comparison of transoral vestibular robotic thyroidectomy with traditional low-collar incision thyroidectomy
Transoral vestibular robotic thyroidectomy can really make the patient’s body surface free of scar. This study aimed to compare the surgical and patient-related outcomes between the transoral vestibular roboti...
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Article
Variable projection algorithms with sparse constraint for separable nonlinear models
Separable nonlinear models are widely used in various fields such as time series analysis, system modeling, and machine learning, due to their flexible structures and ability to capture nonlinear behavior of d...
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Article
Open AccessIn vivo assembly enhanced binding effect augments tumor specific ferroptosis therapy
Emerging evidence indicates that the activation of ferroptosis by glutathione peroxidase 4 (GPX4) inhibitors may be a prominent therapeutic strategy for tumor suppression. However, the wide application of GPX4...
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Chapter and Conference Paper
Numerical Investigation of the Effect of Aircraft Nose Wall Waviness on the Hole Pressure of the Static Pressure Probe
The existence of the aircraft nose skin waviness will affect the static pressure measurement, and then affect the altitude indication of aircraft. So it is of great significance to study the effect of waviness...
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Article
Open AccessComparative and phylogenetic analysis of Chiloschista (Orchidaceae) species and DNA barcoding investigation based on plastid genomes
Chiloschista (Orchidaceae, Aeridinae) is an epiphytic leafless orchid that is mainly distributed in tropical or subtropical forest canopies. This rare and threatened orchid lacks molecular resources for phylogene...
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Article
Production of all-male non-transgenic zebrafish by conditional primordial germ cell ablation
Many fish species exhibit remarkable sexual dimorphism, with males possessing numerous advantageous traits for commercial production by aquaculture such as faster growth rate, more efficient food energy utiliz...
