14 Result(s)
within
**ng Pei Hao
Microarrays
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Article
Open AccessIn silico discovery of human natural antisense transcripts
Several high-throughput searches for ppotential natural antisense transcripts (NATs) have been performed recently, but most of the reports were focused on cis type. A thorough in silico analysis of human transcri...
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Open AccessDiscovering multiple transcripts of human hepatocytes using massively parallel signature sequencing (MPSS)
The liver is the largest human internal organ – it is composed of multiple cell types and plays a vital role in fulfilling the body's metabolic needs and maintaining homeostasis. Of these cell types the hepato...
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Open AccessHuman gene expression sensitivity according to large scale meta-analysis
Genes show different sensitivities in expression corresponding to various biological conditions. Systematical study of this concept is required because of its important implications in microarray analysis etc....
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Open AccessGEOGLE: context mining tool for the correlation between gene expression and the phenotypic distinction
In the post-genomic era, the development of high-throughput gene expression detection technology provides huge amounts of experimental data, which challenges the traditional pipelines for data processing and a...
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Open AccessRevealing parasite influence in metabolic pathways in Apicomplexa infected patients
As an obligate intracellular parasite, Apicomplexa interacts with the host in the special living environment, competing for energy and nutrients from the host cells by manipulating the host metabolism. Previou...
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Open AccessAssociation of tissue lineage and gene expression: conservatively and differentially expressed genes define common and special functions of tissues
Embryogenesis is the process by which the embryo is formed, develops, and establishes developmental hierarchies of tissues. The recent advance in microarray technology made it possible to investigate the tissu...
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Open AccessOptimizing de novo transcriptome assembly from short-read RNA-Seq data: a comparative study
With the fast advances in nextgen sequencing technology, high-throughput RNA sequencing has emerged as a powerful and cost-effective way for transcriptome study. De novo assembly of transcripts provides an import...
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Open AccessGlobal transcriptome analysis reveals extensive gene remodeling, alternative splicing and differential transcription profiles in non-seed vascular plant Selaginella moellendorffii
Selaginella moellendorffii, a lycophyte, is a model plant to study the early evolution and development of vascular plants. As the first and only sequenced lycophyte to date, the genome...
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Open AccessDifferential responses of innate immunity triggered by different subtypes of influenza a viruses in human and avian hosts
Innate immunity provides first line of defense against viral infections. The interactions between hosts and influenza A virus and the response of host innate immunity to viral infection are critical determinan...
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Open AccessA comprehensive study on cellular RNA editing activity in response to infections with different subtypes of influenza a viruses
RNA editing is an important mechanism that expands the diversity and complexity of genetic codes. The conversions of adenosine (A) to inosine (I) and cytosine (C) to uridine (U) are two prominent types of RNA ...
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Open AccessA survey on cellular RNA editing activity in response to Candida albicans infections
Adenosine-to-Inosine (A-to-I) RNA editing is catalyzed by the adenosine deaminase acting on RNA (ADAR) family of enzymes, which induces alterations in mRNA sequence. It has been shown that A-to-I RNA editing e...
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Open AccessMicrobiota in the apical root canal system of tooth with apical periodontitis
Apical periodontitis (AP) is essentially an inflammatory disease of microbial etiology primarily caused by infection of the pulp and root canal system. Variation of the bacterial communities caused by AP, as w...
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Open AccessscSensitiveGeneDefine: sensitive gene detection in single-cell RNA sequencing data by Shannon entropy
Single-cell RNA sequencing (scRNA-seq) is the most widely used technique to obtain gene expression profiles from complex tissues. Cell subsets and developmental states are often identified via differential gen...
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Open AccessRapid screening and identification of viral pathogens in metagenomic data
Virus screening and viral genome reconstruction are urgent and crucial for the rapid identification of viral pathogens, i.e., tracing the source and understanding the pathogenesis when a viral outbreak occurs....
