758 Result(s)

Article

An integrated single-cell RNA-seq map of human neuroblastoma tumors and preclinical models uncovers divergent mesenchymal-like gene expression programs

Neuroblastoma is a common pediatric cancer, where preclinical studies suggest that a mesenchymal-like gene expression program contributes to chemotherapy resistance. However, clinical outcomes remain poor, imp...

Richard H. Chapple, Xueying Liu, Sivaraman Natarajan… in Genome Biology (2024)

Article

A comprehensive analysis of the WRKY family in soybean and functional analysis of GmWRKY164-GmGSL7c in resistance to soybean mosaic virus

Soybean mosaic disease caused by soybean mosaic virus (SMV) is one of the most devastating and widespread diseases in soybean producing areas worldwide. The WRKY transcription factors (TFs) are widely involved in...

Zhihua Zhao, Rongna Wang, Weihua Su, Tianjie Sun, Mengnan Qi, Xueyan Zhang… in BMC Genomics (2024)

Article

LABS: linear amplification-based bisulfite sequencing for ultrasensitive cancer detection from cell-free DNA

Methylation-based liquid biopsies show promises in detecting cancer using circulating cell-free DNA; however, current limitations impede clinical application. Most assays necessitate substantial DNA inputs, po...

**ao-Long Cui, Ji Nie, Houxiang Zhu, Krissana Kowitwanich… in Genome Biology (2024)

Article

Transcriptome analysis reveals the key role of overdominant expression of photosynthetic and respiration-related genes in the formation of tobacco(Nicotiana tabacum L.) biomass heterosis

Leaves are the nutritional and economic organs of tobacco, and their biomass directly affects tobacco yield and the economic benefits of farmers. In the early stage, our research found that tobacco hybrids hav...

Anbin Lu, Shuaibo Zeng, Kai Pi, Benshan Long, Zejun Mo, Renxiang Liu in BMC Genomics (2024)

Article

CsABCG11.2 mediates theanine uptake to alleviate cadmium toxicity in tea plants (Camellia sinensis)

Theanine (Thea) is a unique metabolite in tea plants, but its physiological functions remain elusive. A low soil pH increases cadmium (Cd) availability, affecting the quality of tea plant products. In this stu...

Xulei Hao, Long **ahou, Hanyang Zhao, Jiatong Liu, Fei Guo… in Horticulture Advances (2024)

Article

Structural variant landscapes reveal convergent signatures of evolution in sheep and goats

Sheep and goats have undergone domestication and improvement to produce similar phenotypes, which have been greatly impacted by structural variants (SVs). Here, we report a high-quality chromosome-level refere...

Ji Yang, Dong-Feng Wang, Jia-Hui Huang, Qiang-Hui Zhu, Ling-Yun Luo… in Genome Biology (2024)

Article

Integrating machine learning and genome editing for crop improvement

Genome editing is a promising technique that has been broadly utilized for basic gene function studies and trait improvements. Simultaneously, the exponential growth of computational power and big data now pro...

Long Chen, Guanqing Liu, Tao Zhang in aBIOTECH (2024)

Article

Genome-wide identification and expression analysis of the SPL transcription factor family and its response to abiotic stress in Pisum sativum L

Squamous promoter binding protein-like (SPL) genes encode plant-specific transcription factors (TFs) that play essential roles in modulating plant growth, development, and stress response. Pea (Pisum sativum L.) ...

Long Li, Jian bo Xu, Zhi wen Zhu, Rui Ma, **ao zong Wu, Yu ke Geng in BMC Genomics (2024)

Article

Identification of Eleutherococcus senticosus NAC transcription factors and their mechanisms in mediating DNA methylation of EsFPS, EsSS, and EsSE promoters to regulate saponin synthesis

The formation of pharmacologically active components in medicinal plants is significantly impacted by DNA methylation. However, the exact mechanisms through which DNA methylation regulates secondary metabolism...

**g Dong, Xuelei Zhao, **n Song, Shuo Wang, Xueying Zhao, Baoxiang Liang… in BMC Genomics (2024)

Article

A high-quality haplotype genome of Michelia alba DC reveals differences in methylation patterns and flower characteristics

Michelia alba DC is a highly valuable ornamental plant of the Magnoliaceae family. This evergreen tropical tree commonly grows in Southeast Asia and is adored for its delightful fragrance. Our study assembled the...

Sirong Jiang, Meiling Zou, Chenji Zhang, wanfeng Ma, Chengcai **a… in Molecular Horticulture (2024)

Article

Isochorismate synthase is required for phylloquinone, but not salicylic acid biosynthesis in rice

Salicylic acid (SA) is a phytohormone required for plant growth and defense signaling. There are two major SA biosynthesis pathways in plants: the isochorismate synthase (ICS) pathway and the phenylalanine amm...

Zengqian Wang, Guiqing Yang, Dandan Zhang, Guangxin Li, **-Long Qiu, Jie Wu in aBIOTECH (2024)

Article

Expression patterns and evidence of the expansion of Nicotiana tabacum L. TALE genes in the Solanaceae family

The three-amino-acid-loop-extension (TALE) proteins are a class of transcription factors that regulate meristem differentiation during plant growth and development. In this study, we identified a total of 45 m...

Yanru Song, Decai Kong, Youqing Dai, Kangkang Song… in Genetic Resources and Crop Evolution (2024)

Article

Retraction Note: Comparison of preoperative ultrasound and MRI in the diagnosis of microvascular invasion in hepatocellular carcinoma

Yunmin Long, Zheng Lv, Shaoyi Wang, Bing Tang, Qin Li… in Functional & Integrative Genomics (2024)

Article

Genome-wide identification, molecular evolution and gene expression of P450 gene family in Cyrtotrachelus buqueti

Insect Cytochrome P450 monooxygenase (CYPs or P450s) plays an important role in detoxifying insecticides, causing insect populations to develop resistance. However, the molecular functions of P450 gene family in

Chun Fu, Ding Yang, Wen Cong Long, **Meng **ao, HanYu Wang, Na Jiang… in BMC Genomics (2024)