291 Result(s)

Article

Bacterial c-di-GMP triggers metamorphosis of mussel larvae through a STING receptor

Bacteria induced metamorphosis observed in nearly all marine invertebrates. However, the mechanism of bacteria regulating the larvae-juvenile metamorphosis remains unknown. Here, we test the hypothesis that c-...

**ao-Meng Hu, Lihua Peng, Yuyi Wang, Fan Ma, Yu Tao… in npj Biofilms and Microbiomes (2024)

Article

An integrated single-cell RNA-seq map of human neuroblastoma tumors and preclinical models uncovers divergent mesenchymal-like gene expression programs

Neuroblastoma is a common pediatric cancer, where preclinical studies suggest that a mesenchymal-like gene expression program contributes to chemotherapy resistance. However, clinical outcomes remain poor, imp...

Richard H. Chapple, Xueying Liu, Sivaraman Natarajan… in Genome Biology (2024)

Article

A comprehensive analysis of the WRKY family in soybean and functional analysis of GmWRKY164-GmGSL7c in resistance to soybean mosaic virus

Soybean mosaic disease caused by soybean mosaic virus (SMV) is one of the most devastating and widespread diseases in soybean producing areas worldwide. The WRKY transcription factors (TFs) are widely involved in...

Zhihua Zhao, Rongna Wang, Weihua Su, Tianjie Sun, Mengnan Qi, Xueyan Zhang… in BMC Genomics (2024)

Article

LABS: linear amplification-based bisulfite sequencing for ultrasensitive cancer detection from cell-free DNA

Methylation-based liquid biopsies show promises in detecting cancer using circulating cell-free DNA; however, current limitations impede clinical application. Most assays necessitate substantial DNA inputs, po...

**ao-Long Cui, Ji Nie, Houxiang Zhu, Krissana Kowitwanich… in Genome Biology (2024)

Article

Transcriptome analysis reveals the key role of overdominant expression of photosynthetic and respiration-related genes in the formation of tobacco(Nicotiana tabacum L.) biomass heterosis

Leaves are the nutritional and economic organs of tobacco, and their biomass directly affects tobacco yield and the economic benefits of farmers. In the early stage, our research found that tobacco hybrids hav...

Anbin Lu, Shuaibo Zeng, Kai Pi, Benshan Long, Zejun Mo, Renxiang Liu in BMC Genomics (2024)

Article

Structural variant landscapes reveal convergent signatures of evolution in sheep and goats

Sheep and goats have undergone domestication and improvement to produce similar phenotypes, which have been greatly impacted by structural variants (SVs). Here, we report a high-quality chromosome-level refere...

Ji Yang, Dong-Feng Wang, Jia-Hui Huang, Qiang-Hui Zhu, Ling-Yun Luo… in Genome Biology (2024)

Article

Genome-wide identification and expression analysis of the SPL transcription factor family and its response to abiotic stress in Pisum sativum L

Squamous promoter binding protein-like (SPL) genes encode plant-specific transcription factors (TFs) that play essential roles in modulating plant growth, development, and stress response. Pea (Pisum sativum L.) ...

Long Li, Jian bo Xu, Zhi wen Zhu, Rui Ma, **ao zong Wu, Yu ke Geng in BMC Genomics (2024)

Article

Identification of Eleutherococcus senticosus NAC transcription factors and their mechanisms in mediating DNA methylation of EsFPS, EsSS, and EsSE promoters to regulate saponin synthesis

The formation of pharmacologically active components in medicinal plants is significantly impacted by DNA methylation. However, the exact mechanisms through which DNA methylation regulates secondary metabolism...

**g Dong, Xuelei Zhao, **n Song, Shuo Wang, Xueying Zhao, Baoxiang Liang… in BMC Genomics (2024)

Article

Retraction Note: Comparison of preoperative ultrasound and MRI in the diagnosis of microvascular invasion in hepatocellular carcinoma

Yunmin Long, Zheng Lv, Shaoyi Wang, Bing Tang, Qin Li… in Functional & Integrative Genomics (2024)

Article

Genome-wide identification, molecular evolution and gene expression of P450 gene family in Cyrtotrachelus buqueti

Insect Cytochrome P450 monooxygenase (CYPs or P450s) plays an important role in detoxifying insecticides, causing insect populations to develop resistance. However, the molecular functions of P450 gene family in

Chun Fu, Ding Yang, Wen Cong Long, **Meng **ao, HanYu Wang, Na Jiang… in BMC Genomics (2024)

Article

Bacterial c-di-GMP signaling gene affects mussel larval metamorphosis through outer membrane vesicles and lipopolysaccharides

Biofilms serve as crucial cues for settlement and metamorphosis in marine invertebrates. Within bacterial systems, c-di-GMP functions as a pivotal signaling molecule regulating both biofilm formation and dispe...

**ao-Meng Hu, Lihua Peng, **gxian Wu, Guanju Wu… in npj Biofilms and Microbiomes (2024)

Article

Identification of the principal neuropeptide MIP and its action pathway in larval settlement of the echiuran worm Urechis unicinctus

Larval settlement and metamorphosis represent critical events in the life history of marine benthic animals. Myoinhibitory peptide (MIP) plays a pivotal role in larval settlement of marine invertebrates. Howev...

Zhi Yang, Long Zhang, Wenqing Zhang, **nhua Tian, Wenyuan Lai, Dawei Lin… in BMC Genomics (2024)

Article

Karyotype and LTR-RTs analysis provide insights into oak genomic evolution

Whole-genome duplication and long terminal repeat retrotransposons (LTR-RTs) amplification in organisms are essential factors that affect speciation, local adaptation, and diversification of organisms. Underst...

Rui-Bin Cao, Ran Chen, Ke-**n Liao, He Li, Gang-Biao Xu, **ao-Long Jiang in BMC Genomics (2024)

Article

DNA methylation regulates the secondary metabolism of saponins to improve the adaptability of Eleutherococcus senticosus during drought stress

Plant growth and development can be significantly impacted by drought stress. Plants will adjust the synthesis and accumulation of secondary metabolites to improve survival in times of water constraint. Simult...

Shuo Wang, XueLei Zhao, Chang Li, **g Dong, JiaCheng Ma, YueHong Long… in BMC Genomics (2024)

Article

Photoheterotroph improved the growth and nutrient levels of Chlorella vulgaris and the related molecular mechanism

Microalgae are rich in fatty acids, proteins, and other nutrients, which have gained the general attention of researchers all over the world. For the development of Chlorella vulgaris in food and feed industry, t...

**anmei Long, Cancan Zhang, Qian Yang… in Applied Microbiology and Biotechnology (2024)

Article

Correction to: Transformed Salmonella typhimurium SL7207/pcDNA-CCOL2A1 as an orally administered DNA vaccine

Juan Long, Yang Zeng, Fei Liang, Nan Liu, Yongzhi **, Yuying Sun, **ao Zhao in AMB Express (2024)

Article

Pancreatitis affects gut microbiota via metabolites and inflammatory cytokines: an exploratory two-step Mendelian randomisation study

Previous studies have observed relationships between pancreatitis and gut microbiota; however, specific changes in gut microbiota abundance and underlying mechanisms in pancreatitis remain unknown. Metabolites...

Yi-Fan Qiu, Jun Ye, **-** **e, **ao-Tong Mao… in Molecular Genetics and Genomics (2024)

Article

Complete chloroplast genome and comparison of herbicides toxicity on Aeschynomene indica (Leguminosae) in upland direct-seeding paddy field

Indian jointvetch (Aeschynomene indica) is a common and pernicious weed found in the upland direct-seeding rice fields in the lower reaches of the Yangtze River in China. However, there are few reports on the deg...

Yuan Gao, TianYu Chen, Jiaqi Long, Guohui Shen, Zhihui Tian in BMC Genomics (2024)

Article

Shared and distinct interactions of type 1 and type 2 Epstein-Barr Nuclear Antigen 2 with the human genome

There are two major genetic types of Epstein-Barr Virus (EBV): type 1 (EBV-1) and type 2 (EBV-2). EBV functions by manipulating gene expression in host B cells, using virus-encoded gene regulatory proteins inc...

Kenyatta C. M. F. Viel, Sreeja Parameswaran, Omer A. Donmez… in BMC Genomics (2024)

Article

Expression, purification, and characterization of transmembrane protein homogentisate solanesyltransferase

Homogentisate solanesyltransferase (HST) is a crucial enzyme in the plastoquinone biosynthetic pathway and has recently emerged as a promising target for herbicides. In this study, we successfully expressed an...

Han **ao, Long-Can Mei, Hong-Yan Lin, Zhao Chen… in Applied Microbiology and Biotechnology (2024)