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4,471 Result(s)
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Article
Correction: Empaglifozin improves kidney senescence induced by d-galactose by reducing sirt1-mediated oxidative stress
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Open AccessIncreased ONECUT2 induced by Helicobacter pylori promotes gastric cancer cell stemness via an AKT-related pathway
Helicobacter pylori (HP) infection initiates and promotes gastric carcinogenesis. ONECUT2 shows promise for tumor diagnosis, prognosis, and treatment. This study explored ONECUT2’s role and the specific mechanism...
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Analysis of Transcriptome Differences in the Root System, Leaves, and Corms between Healthy and Fusarium Wilt-Diseased Baodaojiao Banana Plants
Banana Fusarium wilt is a devastating disease threatening the production of many agricultural plants, with no effective and radical control measures identified and applied to date. At present, one of the most ...
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Isolation and characterization of three DREB-like genes encoding dehydration-responsive element binding proteins in chicory (Cichorium intybus)
Three novel DREB (Dehydration-Responsive Element Binding protein) genes, designated as CiDREB2A, CiDREB5A and CiDREB6A, were individually isolated from chicory (Cichorium intybus L). Based on phylogenetic tree an...
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Open AccessBiocontrol potential and growth-promoting effect of endophytic fungus Talaromyces muroii SD1-4 against potato leaf spot disease caused by Alternaria alternata
Alternaria alternata is the primary pathogen of potato leaf spot disease, resulting in significant potato yield losses globally. Endophytic microorganism-based biological control, especially using microorganisms ...
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Cold tolerance SNPs and candidate gene mining in the soybean germination stage based on genome-wide association analysis
Three QTLs associated with low-temperature tolerance were identified by genome-wide association analysis, and 15 candidate genes were identified by haplotype analysis and gene expression analyses.
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Predicting the rate of spread of mixed-fuel surface fires in northeastern China using the Rothermel wildfire behaviour model: a laboratory study
The rate of fire spread is a key indicator for assessing forest fire risk and develo** fire management plans. The Rothermel model is the most widely used fire spread model, established through laboratory exp...
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Open AccessRSL3 enhances ROS-mediated cell apoptosis of myelodysplastic syndrome cells through MYB/Bcl-2 signaling pathway
Myelodysplastic syndromes (MDS) are clonal hematopoietic malignancies and seriously threaten people’s health. Current therapies include bone marrow transplantation and several hypomethylating agents. However, ...
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Open AccessThe circadian gene ARNTL2 promotes nasopharyngeal carcinoma invasiveness and metastasis through suppressing AMOTL2-LATS-YAP pathway
Metastasis is the major culprit of treatment failure in nasopharyngeal carcinoma (NPC). Aryl hydrocarbon receptor nuclear translocator like 2 (ARNTL2), a core circadian gene, plays a crucial role in the develo...
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Chronic Fluoride Exposure Induces Ovarian Dysfunction and Potential Association with Premature Ovarian Failure in Female Rats
Chronic fluorosis has been widely investigated for its adverse effects on skeletal and neurological health; however, its impact on reproductive health, especially in females, remains underexplored. In this stu...
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Author Correction: Urbanization, climate and species traits shape mammal communities from local to continental scales
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Article
Construction of short synthetic promoters for optimization of ovalbumin expression level in Saccharomyces cerevisiae
Saccharomyces cerevisiae, a common eukaryotic model microorganism that is generally recognized as safe, is widely employed for the heterologous expression of edible and therapeutic proteins. Promoters are crucial...
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Article
A clock for clonal organisms
Estimating age in clonal populations is exceedingly challenging, but a study proposes a molecular clock based on genome-wide fixed somatic variations as a solution.
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Article
Single-cell sequencing advances in research on mesenchymal stem/stromal cells
Mesenchymal stem/stromal cells (MSCs), originating from the mesoderm, represent a multifunctional stem cell population capable of differentiating into diverse cell types and exhibiting a wide range of biologic...
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Construction of a plasmid-free Escherichia coli strain for lacto-N-neotetraose biosynthesis
Lacto-N-neotetraose (LNnT), with promising bioactive properties, is one of the most significant nonfucosylated human milk saccharides. Recently, its synthesis by microbial fermentation has attracted great attenti...
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Amphidiploid production of a distant hybrid Populus simonii × P. euphratica cv. ‘**aohuyang-1’ and resulting in phenotypic variation
Populus simonii × P. euphratica cv. ‘**aohuyang-1’ is an elite variety produced by distant hybridization between Populus section Tacamahaca and sect. Turanga. However, its highly gametic sterility makes it diffic...
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Two new species of the deepwater cardinalfish genus Epigonus (Epigonidae) from deep reefs off Curaçao, southern Caribbean
Two new species of deepwater cardinalfish, Epigonus gemma [7 specimens, 37.7–76.7 mm in standard length (SL)] and Epigonus hexacanthus (22 specimens, 32.2–57.0 mm SL) are described based on specimens from deep re...
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Adaptation of a prey population to increasing predation risks
To test the hypotheses that multigenerational predation risk favors clones with longer postero-lateral spines and a larger body, and that fitness consequences of selection depend on both tested fitness variabl...
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Open AccessTime since fire affects ecological stoichiometry of plant–soil–microbial systems of Betula platyphylla, a pioneer species in burnt areas of China’s boreal forest
Plant stoichiometry and nutrient allocation may reflect adaptation strategies to environmental nutrient changes. Fire, as a major disturbance in forests, mediates soil nutrient availability that may influence ...
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Article
Thioclava litoralis sp. nov., a novel species of alphaproteobacterium, isolated from surface seawater
A Gram-negative, aerobic, rod-shaped, non-motile bacterium, designated as FTW29T, was isolated from surface seawater sampled in Futian district, Shenzhen, China. Growth of strain FTW29T was observed at 15–42 ℃ (o...