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1,517 Result(s)
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Article
Open AccessComparing survival outcomes between neoadjuvant and adjuvant chemotherapy within T2N1M0 stage hormone receptor-positive, HER2-negative breast cancer: a retrospective cohort study based on SEER database
Guideline recommendations for the application of neoadjuvant chemotherapy (NACT) in T2N1M0 stage hormone receptor-positive, HER2-negative (HR + /HER2-) breast cancer are ambiguous. The debate continues regardi...
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Article
Open AccessThe correlation between KRAS and TP53 gene mutations and early growth of pulmonary nodules
The purpose of this study is to investigate whether gene mutations can lead to the growth of malignant pulmonary nodules.
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Open AccessRacial Fairness of Individual- and Community-Level Proxies of Socioeconomic Status Among Birthing Parent–Child Dyads
While precision medicine algorithms can be used to improve health outcomes, concerns have been raised about racial equity and unintentional harm from encoded biases. In this study, we evaluated the fairness of...
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Open AccessFactors influencing fatigue, mental workload and burnout among Chinese health care workers during public emergencies: an online cross-sectional study
The purpose of this study was to investigate fatigue, mental workload, and burnout among health care workers (HCWs) and explore the possible underlying factors.
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Open AccessA network meta-analysis of psychological interventions for children and adolescents after natural and man-made disasters
Children and adolescents, after natural and man-made disasters, often exhibit various psychological, emotional, and behavioral issues, showing a range of clinical symptoms related to post-traumatic stress diso...
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Open AccessLINC00525 enhances ZNF460-regulated CD24 expression through the sponge miR-125a-5p to promote malignant progression of breast cancer
CD24 is a highly glycosylated glycosylphosphatidylinositol anchored membrane protein that plays an important role in tumor progression. The aim of this study was to investigate the effect of abnormal expressio...
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Open AccessCorrection: Digital exclusion and cognitive impairment in older people: findings from five longitudinal studies
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Open AccessMassive hemothorax induced by pulmonary arteriovenous malformation rupture: a case report and literature review
Pulmonary arteriovenous malformation (PAVM), also known as pulmonary arteriovenous fistula, is a rare vascular developmental anomaly. Most cases of PAVM are associated with hereditary hemorrhagic telangiectasi...
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Open AccessHiPorfin photodynamic therapy for vaginal high-grade squamous intraepithelial lesion
We aimed to evaluate the efficacy and safety of HiPorfin-photodynamic therapy (PDT) in women with vaginal high-grade squamous intraepithelial Lesion (HSIL).
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Open AccessPrognostic analysis of rectal cancer patients after neoadjuvant chemoradiotherapy: different prognostic factors in patients with different TRGs
The extent of tumor regression varies widely among locally advanced rectal cancer (LARC) patients who receive neoadjuvant chemoradiotherapy (NCRT) followed by total mesorectal excision (TME). The purpose of th...
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Open AccessDcR3-associated risk score: correlating better prognosis and enhanced predictive power in colorectal cancer
Decoy receptor 3 (DcR3), a novel soluble protein belonging to the tumor necrosis factor receptor (TNFR) family, has been previously associated with tumorigenesis in various cancers. However, in our study, we u...
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Open AccessThe association among negative life events, alexithymia, and depressive symptoms in a psychosomatic outpatient sample
Depression is a life-threatening mental health problem. Various factors have been demonstrated to be associated with depressive symptoms, including negative life events (NLEs) and alexithymia. A retrospective ...
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Open AccessGeneration of virtual monoenergetic images at 40 keV of the upper abdomen and image quality evaluation based on generative adversarial networks
Abdominal CT scans are vital for diagnosing abdominal diseases but have limitations in tissue analysis and soft tissue detection. Dual-energy CT (DECT) can improve these issues by offering low keV virtual mono...
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Article
Open AccessDevelopment and validation of a risk prediction model for invasiveness of pure ground-glass nodules based on a systematic review and meta-analysis
Assessing the aggressiveness of pure ground glass nodules early on significantly aids in making informed clinical decisions.
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Open AccessThe quality of bone and paraspinal muscle in the fragility osteoporotic vertebral compression fracture: a comprehensive comparison between different indicators
To evaluate the value of five indicators in predicting OVCF through a retrospective case–control study, and explore the internal correlation of different indicators.
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Open AccessNeoadjuvant camrelizumab (an anti-PD-1 antibody) plus chemotherapy or apatinib (a VEGFR-2 inhibitor) for initially unresectable stage II–III non-small-cell lung cancer: a multicentre, two-arm, phase 2 exploratory study
This multicentre, two-arm, phase 2 study aimed to explore the efficacy and safety of neoadjuvant camrelizumab plus chemotherapy or apatinib in patients with initially unresectable stage II–III non-small-cell l...
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Open AccessEfficacy and safety of once-weekly tirzepatide for weight management compared to placebo: An updated systematic review and meta-analysis including the latest SURMOUNT-2 trial
Tirzepatide, a newly developed dual glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, has received approval for treating type 2 diabetes (T2D) and is currentl...
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Open AccessHow context links to best practice use in long-term care homes: a mixed methods study
Context (work environment) plays a crucial role in implementing evidence-based best practices within health care settings. Context is multi-faceted and its complex relationship with best practice use by care a...
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Open AccessA novel higher performance nomogram based on explainable machine learning for predicting mortality risk in stroke patients within 30 days based on clinical features on the first day ICU admission
This study aimed to develop a higher performance nomogram based on explainable machine learning methods, and to predict the risk of death of stroke patients within 30 days based on clinical characteristics on ...
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Open AccessOptimal ICSI timing on immature oocytes for low prognosis patients under the POSEIDON classification
The optimal timing of performing ICSI on immature oocytes for POSEIDON patients is still unknown to get better early embryonic development outcomes. The purpose of this study was to implore the most appropriat...