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Article
Evolutionary analysis of SLC10 family members and insights into function and expression regulation of lamprey NTCP
The Na ( +)-taurocholate cotransporting polypeptide (NTCP) is a member of the solute carrier family 10 (SLC10), which consists of 7 members (SLC10a1-SLC10a7). NTCP is a transporter localized to the basolateral...
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Article
Network meta-analysis of probiotics, prebiotics, and synbiotics for the treatment of chronic constipation in adults
To compare the outcomes associated with the use of probiotics, prebiotics, and synbiotics for the treatment of chronic constipation in adults.
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Article
Open AccessClinical and metagenomic characteristics of lymphadenopathy related to fever of unknown origin in children
Diagnosis of fever of unknown origin remains challenge for pediatricians. Lymphadenopathy is a separate entity that mainly originates from infection or malignancy.
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Article
Open AccessGlobal annual wetland dataset at 30 m with a fine classification system from 2000 to 2022
Wetlands play a key role in maintaining ecological balance and climate regulation. However, due to the complex and variable spectral characteristics of wetlands, there are no publicly available global 30-meter...
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Article
Deep convolutional encoder–decoder networks based on ensemble learning for semantic segmentation of high-resolution aerial imagery
Due to the complexity of object information and optical conditions of high-resolution aerial imagery, it is difficult to obtain fine semantic segmentation performance. Although various deep neural network stru...
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Article
Open AccessEffect of the mitochondrial uncoupling agent BAM15 against the Toxoplasma gondii RH strain and Prugniaud strain
Toxoplasmosis is a zoonotic disease caused by the infection of the protozoa Toxoplasma gondii (T. gondii), and safe and effective therapeutic drugs are lacking. Mitochondria, is an important organelle that mainta...
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Article
Clinical evaluation of deep learning systems for assisting in the diagnosis of the epiretinal membrane grade in general ophthalmologists
Epiretinal membrane (ERM) is a common age-related retinal disease detected by optical coherence tomography (OCT), with a prevalence of 34.1% among people over 60 years old. This study aims to develop artificia...
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Article
PD-GATv2: positive difference second generation graph attention network based on multi-granularity in information systems to classification
The Graph Attention Network (GAT) is a widely recognized architecture in the field of Graph Neural Networks (GNNs). It is considered the state-of-the-art approach for graph representation learning. In recent y...
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Article
Reporting quality and risk of bias of systematic reviews of ultra-processed foods: a methodological study
A dramatic shift in the global food system is occurring with the rapid growth of ultra-processed foods (UPFs) consumption, which poses potentially serious health risks. Systematic review (SR) method has been u...
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Article
Open AccessConstruction and implementation of wide range parameter switchable chaotic system
Research on switchable chaotic systems with a large range of parameters is scarce. To explore the chaotic characteristics of such systems, this paper proposes new switchable methods by modifying the nonlinear ...
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Article
Open AccessComparison of effectiveness and safety of lasmiditan and CGRP-antagonists for the acute treatment of migraine in adults: systematic review and network meta-analysis of randomised trials
To compare the outcomes associated with the use of lasmiditan, rimegepant, ubrogepant, and zavegepant for the acute management of migraine headaches.
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Article
Surface guided radiation therapy with an innovative open-face mask and mouth bite: patient motion management in brain stereotactic radiotherapy
To guarantee treatment reproducibility and stability, immobilization devices are essential. Additionally, surface-guided radiation therapy (SGRT) serves as an accurate complement to frameless stereotactic radi...
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Article
Highly Stretchable, Sensitive, and Multifunctional Thermoelectric Fabric for Synergistic-Sensing Systems of Human Signal Monitoring
Stretchable thermoelectric-based self-powered sensors have attracted widespread attention for wearable electronic devices. However, the development of thermoelectric materials with wearable comfort, green, and...
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Article
Open AccessAntigen presenting cells in cancer immunity and mediation of immune checkpoint blockade
Antigen-presenting cells (APCs) are pivotal mediators of immune responses. Their role has increasingly been spotlighted in the realm of cancer immunology, particularly as our understanding of immunotherapy con...
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Article
Open AccessUnraveling the intercellular communication disruption and key pathways in Alzheimer’s disease: an integrative study of single-nucleus transcriptomes and genetic association
Recently, single-nucleus RNA-seq (snRNA-seq) analyses have revealed important cellular and functional features of Alzheimer's disease (AD), a prevalent neurodegenerative disease. However, our knowledge regardi...
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Chapter and Conference Paper
Bayesian Optimization for Auto-tuning Convolution Neural Network on GPU
GPU as a hardware processor plays an important role in the training of deep neural networks. However, when using GPUs for computation on convolutional neural network models, different combinations of GPU kerne...
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Chapter and Conference Paper
Building an Economic Argumentation Model for Vessel Train
Vessel train has emerged as an innovative mode of transport organization and also as an intelligent ship-navigating technique. In this paper, we focus on the economic efficiency of vessel train for inland ship...
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Chapter
Ammonia Combustion Enhancement
The use of ammonia as a fuel has been recognized as a promising way for various energy and power devices toward carbon neutrality. However, significantly different combustion characteristics of ammonia from co...
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Article
Open AccessDissecting the tumor microenvironment in response to immune checkpoint inhibitors via single-cell and spatial transcriptomics
Cancer is a disease that undergoes selective pressure to evolve during its progression, becoming increasingly heterogeneous. Tumoral heterogeneity can dictate therapeutic response. Transcriptomics can be used ...
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Article
Open AccessThe mechanism of linear ubiquitination in regulating cell death and correlative diseases
Linear ubiquitination is a specific post-translational modification in which ubiquitin is linked through M1 residue to form multiple types of polyubiquitin chains on substrates in order to regulate cellular pr...
